skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Title: Improved Training Paradigms and Motor-decode Algorithms: Results from Intact Individuals and a Recent Transradial Amputee with Prior Complex Regional Pain Syndrome
Working towards improved neuromyoelectric control of dexterous prosthetic hands, we explored how differences in training paradigms affect the subsequent online performance of two different motor-decode algorithms. Participants included two intact subjects and one participant who had undergone a recent transradial amputation after complex regional pain syndrome (CRPS) and multi-year disuse of the affected hand. During algorithm training sessions, participants actively mimicked hand movements appearing on a computer monitor. We varied both the duration of the hold-time (0.1 s or 5 s) at the end-point of each of six different digit and wrist movements, and the order in which the training movements were presented (random or sequential). We quantified the impact of these variations on two different motordecode algorithms, both having proportional, six-degree-offreedom (DOF) control: a modified Kalman filter (MKF) previously reported by this group, and a new approach - a convolutional neural network (CNN). Results showed that increasing the hold-time in the training set improved run-time performance. By contrast, presenting training movements in either random or sequential order had a variable and relatively modest effect on performance. The relative performance of the two decode algorithms varied according to the performance metric. This work represents the first-ever amputee use of a CNN for real-time, proportional six-DOF control of a prosthetic hand. Also novel was the testing of implanted high-channelcount devices for neuromyoelectric control shortly after amputation, following CRPS and long-term hand disuse. This work identifies key factors in the training of decode algorithms that improve their subsequent run-time performance.  more » « less
Award ID(s):
1533649
PAR ID:
10121188
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Volume:
0
Issue:
0
Page Range / eLocation ID:
3782 to 3787
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. Intuitive control of prostheses relies on training algorithms to correlate biological recordings to motor intent. The quality of the training dataset is critical to run-time performance, but it is difficult to label hand kinematics accurately after the hand has been amputated. We quantified the accuracy and precision of labeling hand kinematics for two different approaches: 1) assuming a participant is perfectly mimicking predetermined motions of a prosthesis (mimicked training), and 2) assuming a participant is perfectly mirroring their contralateral hand during identical bilateral movements (mirrored training). We compared these approaches in non-amputee individuals, using an infrared camera to track eight different joint angles of the hands in real-time. Aggregate data revealed that mimicked training does not account for biomechanical coupling or temporal changes in hand posture. Mirrored training was significantly more accurate and precise at labeling hand kinematics. However, when training a modified Kalman filter to estimate motor intent, the mimicked and mirrored training approaches were not significantly different. The results suggest that the mirrored training approach creates a more faithful but more complex dataset. Advanced algorithms, more capable of learning the complex mirrored training dataset, may yield better run-time prosthetic control. 
    more » « less
  2. Myoelectric control of prostheses is a long-established technique, using surface electromyography (sEMG) to detect user intention and perform subsequent mechanical actions. Most machine learning models utilized in control systems are trained using isolated movements that do not reflect the natural movements occurring during daily activities. Moreover, movements are often affected by arm postures, the duration of activities, and personal habits. It is crucial to have a control system for multi-degree-of-freedom (DoF) prosthetic arms that is trained using sEMG data collected from activities of daily living (ADL) tasks. This work focuses on two major functional wrist movements: pronation-supination and dart-throwing movement (DTM), and introduces a new wrist control system that directly maps sEMG signals to the joint velocities of the multi-DoF wrist. Additionally, a specific training strategy (Quick training) is proposed that enables the controller to be applied to new subjects and handle situations where sensors may displace during daily living, muscles can become fatigued, or sensors can become contaminated (e.g., due to sweat). The prosthetic wrist controller is designed based on data from 24 participants and its performance is evaluated using the Root Mean Square Error (RMSE) and Pearson Correlation. The results are found to depend on the characteristics of the tasks. For example, tasks with dart-throwing motion show smaller RSME values (Hammer: 6.68 deg/s and Cup: 7.92 deg/s) compared to tasks with pronation-supination (Bulb: 43.98 deg/s and Screw: 53.64 deg/s). The proposed control technique utilizing Quick training demonstrates a decrease in the average root mean square error (RMSE) value by 35% and an increase in the average Pearson correlation value by 40% across all four ADL tasks. 
    more » « less
  3. Abstract Despite the rapid progress and interest in brain-machine interfaces that restore motor function, the performance of prosthetic fingers and limbs has yet to mimic native function. The algorithm that converts brain signals to a control signal for the prosthetic device is one of the limitations in achieving rapid and realistic finger movements. To achieve more realistic finger movements, we developed a shallow feed-forward neural network to decode real-time two-degree-of-freedom finger movements in two adult male rhesus macaques. Using a two-step training method, a recalibrated feedback intention–trained (ReFIT) neural network is introduced to further improve performance. In 7 days of testing across two animals, neural network decoders, with higher-velocity and more natural appearing finger movements, achieved a 36% increase in throughput over the ReFIT Kalman filter, which represents the current standard. The neural network decoders introduced herein demonstrate real-time decoding of continuous movements at a level superior to the current state-of-the-art and could provide a starting point to using neural networks for the development of more naturalistic brain-controlled prostheses. 
    more » « less
  4. We describe use of a bidirectional neuromyoelectric prosthetic hand that conveys biomimetic sensory feedback. Electromyographic recordings from residual arm muscles were decoded to provide independent and proportional control of a six-DOF prosthetic hand and wrist—the DEKA LUKE arm. Activation of contact sensors on the prosthesis resulted in intraneural microstimulation of residual sensory nerve fibers through chronically implanted Utah Slanted Electrode Arrays, thereby evoking tactile percepts on the phantom hand. With sensory feedback enabled, the participant exhibited greater precision in grip force and was better able to handle fragile objects. With active exploration, the participant was also able to distinguish between small and large objects and between soft and hard ones. When the sensory feedback was biomimetic—designed to mimic natural sensory signals—the participant was able to identify the objects significantly faster than with the use of traditional encoding algorithms that depended on only the present stimulus intensity. Thus, artificial touch can be sculpted by patterning the sensory feedback, and biologically inspired patterns elicit more interpretable and useful percepts. 
    more » « less
  5. Abstract Electromyogram (EMG) has been a fundamental approach for prosthetic hand control. However it is limited by the functionality of residual muscles and muscle fatigue. Currently, exploring temporal shifts in brain networks and accurately classifying noninvasive electroencephalogram (EEG) for prosthetic hand control remains challenging. In this manuscript, it is hypothesized that the coordinated and synchronized temporal patterns within the brain network, termed as brain synergy, contain valuable information to decode hand movements. 32-channel EEGs were acquired from 10 healthy participants during hand grasp and open. Synergistic spatial distribution pattern and power spectra of brain activity were investigated using independent component analysis of EEG. Out of 32 EEG channels, 15 channels spanning the frontal, central and parietal regions were strategically selected based on the synergy of spatial distribution pattern and power spectrum of independent components. Time-domain and synergistic features were extracted from the selected 15 EEG channels. These features were employed to train a Bayesian optimizer-based support vector machine (SVM). The optimized SVM classifier could achieve an average testing accuracy of 94.39$$ \pm $$.84% using synergistic features. The pairedt-test showed that synergistic features yielded significantly higher area under curve values (p < .05) compared to time-domain features in classifying hand movements. The output of the classifier was employed for the control of the prosthetic hand. This synergistic approach for analyzing temporal activities in motor control and control of prosthetic hands have potential contributions to future research. It addresses the limitations of EMG-based approaches and emphasizes the effectiveness of synergy-based control for prostheses. 
    more » « less