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Abstract. The International Monitoring System (IMS) was established in the late 1990sfor verification of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Uponcompletion, 60 infrasound stations distributed over the globe will monitorthe Earth's atmosphere for low-frequency pressure waves. In this study, wepresent advanced infrasound data products of the 53 currently certified IMSinfrasound stations for atmospheric studies and civilian applications. Forthis purpose, 18 years of raw IMS infrasound waveform data (2003–2020) were reprocessed using the Progressive Multi-Channel Correlation (PMCC) method. A one-third octave frequency band configuration between 0.01 and 4 Hz was chosen to run this array-processing algorithm which detects coherent infrasound waves within the background noise. From the comprehensive detection lists, four products were derived for each of the certified 53 IMS infrasound stations. The four products cover different frequency ranges and are provided at the following different temporal resolutions: a very low-frequency set (0.02–0.07 Hz, 30 min; https://doi.org/10.25928/bgrseis_bblf-ifsd, Hupe et al., 2021a), two so-called microbarom frequency sets – covering both the lower (0.15–0.35 Hz, 15 min; https://doi.org/10.25928/bgrseis_mblf-ifsd, Hupe et al., 2021b) and a higher (0.45–0.65 Hz, 15 min; https://doi.org/10.25928/bgrseis_mbhf-ifsd, Hupe et al., 2021c) part – named after the dominant ambient noise of interacting ocean waves that are quasi-continuously detected at IMS stations, and observations with center frequencies of 1 to 3 Hz (5 min), called the high-frequency product (https://doi.org/10.25928/bgrseis_bbhf-ifsd, Hupe et al., 2021d). Within these frequency ranges and time windows, the dominant repetitive signal directions are summarized. Along with several detection parameters, calculated quantities for assessing the relative quality of the products are provided. The validity of the data products is demonstrated through example case studies of recent events that produced infrasound detected at IMS infrasound stations and through a global assessment and summary of the products. The four infrasound data products cover globally repeating infrasound sources such as ocean ambient noise or persistently active volcanoes, which have previously been suggested as sources for probing the winds in the middle atmosphere. Therefore, our infrasound data products open up the IMS observations also to user groups who do not have unconstrained access to IMS data or who are unfamiliar with infrasound data processing using the PMCC method. These types of data products could potentially serve as a basis for volcanic eruption early warning systems in the future.
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Imaging mass spectrometry for natural products discovery: a review of ionization methods
Covering: 2009–2019 Over the last decade, methods in imaging mass spectrometry (IMS) have progressively improved and diversified toward a variety of applications in natural products research. Because IMS allows for the spatial mapping of the production and distribution of biologically active molecules in situ , it facilitates phenotype and organelle driven discovery efforts. As practitioners of IMS for natural products discovery, we find one of the most important aspects of these experiments is the sample preparation and compatibility with different ionization sources that are available to a given researcher. As such, we have focused this mini review to cover types of ionization sources that have been used in natural products discovery applications and provided concrete examples of use for natural products discovery while discussing the advantages and limitations of each method. We aim for this article to serve as a resource to guide the broader natural product community interested in IMS toward the application/method that would best serve their natural product discovery needs given the sample and analyte(s) of interest. This mini review has been limited to applications using natural products and thus is not exhaustive of all possible ionization methods which have only been applied to image other types of samples such as mammalian tissues. Additionally, we briefly review how IMS has been coupled with other imaging platforms, such as microscopy, to enhance information outputs as well as offer our future perspectives on the incorporation of IMS in natural products discovery.
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- Award ID(s):
- 1817955
- PAR ID:
- 10132580
- Date Published:
- Journal Name:
- Natural Product Reports
- ISSN:
- 0265-0568
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1039/c9np00038k
