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1. Long G4-rich enhancers target promoters via a G4 DNA-based mechanism

   https://doi.org/10.1093/nar/gkae1180  

   DeMeis, Jeffrey D.; Roberts, Justin T.; Delcher, Haley A.; Godang, Noel L.; Coley, Alexander B.; Brown, Cana L.; Shaw, Michael H.; Naaz, Sayema; Dahal, Ayush; Alqudah, Shahem Y.; et al (December 2024, Nucleic Acids Research)

   Abstract Several studies have now described instances where G-rich sequences in promoters and enhancers regulate gene expression through forming G-quadruplex (G4) structures. Relatedly, our group recently identified 301 long genomic stretches significantly enriched for minimal G4 motifs (LG4s) in humans and found the majority of these overlap annotated enhancers, and furthermore, that the promoters regulated by these LG4 enhancers are similarly enriched with G4-capable sequences. While the generally accepted model for enhancer:promoter specificity maintains that interactions are dictated by enhancer- and promoter-bound transcriptional activator proteins, the current study tested an alternative hypothesis: that LG4 enhancers interact with cognate promoters via a direct G4:G4 DNA-based mechanism. This work establishes the nuclear proximity of LG4 enhancer:promoter pairs, biochemically demonstrates the ability of individual LG4 single-stranded DNAs (ssDNAs) to directly interact target promoter ssDNAs, and confirms that these interactions, as well as the ability of LG4 enhancers to activate target promoters in culture, are mediated by G4 DNA. 

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2. Robotics-based Engineering Approaches in the G4-12 Curriculum

   Dopp, D.; Bergin, D. A.; Nair, S.S. (July 2021, 2021 Americal Society for Engineering Education Annual Conference)

   The paper introduces software and control concepts from an automation point of view to K-12 students, via LEGO robotics 

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3. Transferable MP2-Based Machine Learning for Accurate Coupled-Cluster Energies

   https://doi.org/10.1021/acs.jctc.0c00927  

   Townsend, Jacob; Vogiatzis, Konstantinos D. (December 2020, Journal of Chemical Theory and Computation)

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4. Improving MP2 bandgaps with low-scaling approximations to EOM-CCSD

   https://doi.org/10.1063/5.0061242  

   Lange, Malte F.; Berkelbach, Timothy C. (August 2021, The Journal of Chemical Physics)

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5. MAP: An MP2 Accuracy Predictor for Weak Interactions from Adiabatic Connection Theory

   https://doi.org/10.1021/acs.jctc.0c00049  

   Vuckovic, Stefan; Fabiano, Eduardo; Gori-Giorgi, Paola; Burke, Kieron (July 2020, Journal of Chemical Theory and Computation)

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