Contamination occurs in observational research on child maltreatment when individuals assigned to a comparison condition have, unbeknownst to investigators, been exposed to maltreatment. Contamination is a major threat because it biases the statistical significance and magnitude of maltreatment effects, leading to replication failures and an underestimation of the public health impacts of child maltreatment. Despite its presence, there are no established solutions for addressing contamination in child maltreatment research. This symposium brings together leading experts who will present cutting-edge research addressing a range of critical topics for detecting and correcting contamination in observational research on child maltreatment: 1) a conceptual foundation for what contamination is and how it occurs, 2) the prevalence of contamination across independent and international research, 3) the impact contamination has on the direction, statistical significance, and magnitude of maltreatment effects for a range of public health outcomes in nationally-representative and multi-wave designs, and 4) innovative methodological solutions for detecting and correcting contamination. This symposium will provide needed information for child maltreatment researchers to correct contamination in observational research and improve the accuracy, and therefore replicability, of casual effects across public health outcomes. A formal discussion and integration of results presented in this symposium will also aid trauma researchers at large, as contamination can occur in any observational research design.
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BRAIN Initiative: Cutting-Edge Tools and Resources for theCommunity
The overarching goal of the NIH BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative is to advance theunderstanding of healthy and diseased brain circuit function through technological innovation. Core principles for this goal include thevalidation and dissemination of the myriad innovative technologies, tools, methods, and resources emerging from BRAIN-fundedresearch. Innovators, BRAIN funding agencies, and non-Federal partners are working together to develop strategies for making theseproducts usable, available, and accessible to the scientific community. Here, we describe several early strategies for supporting thedissemination of BRAIN technologies. We aim to invigorate a dialogue with the neuroscience research and funding community, inter-disciplinary collaborators, and trainees about the existing and future opportunities for cultivating groundbreaking research productsinto mature, integrated, and adaptable research systems. Along with the accompanying Society for Neuroscience 2019 Mini-Symposium,“BRAIN Initiative: Cutting-Edge Tools and Resources for the Community,” we spotlight the work of several BRAIN investigator teamswho are making progress toward providing tools, technologies, and services for the neuroscience community. These tools access neuralcircuits at multiple levels of analysis, from subcellular composition to brain-wide network connectivity, including the following: inte-grated systems for EM- and florescence-based connectomics, advances in immunolabeling capabilities, and resources for recording andanalyzing functional connectivity. Investigators describe how the resources they provide to the community will contribute to achievingthe goals of the NIH BRAIN Initiative. Finally, in addition to celebrating the contributions of these BRAIN-funded investigators, theMini-Symposium will illustrate the broader diversity of BRAIN Initiative investments in cutting-edge technologies and resources.
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- Award ID(s):
- 1707356
- PAR ID:
- 10171026
- Date Published:
- Journal Name:
- The journal of neuroscience
- Volume:
- 39
- Issue:
- 42
- ISSN:
- 0270-6474
- Page Range / eLocation ID:
- 8275– 8284
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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