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1. Environmental Factors and Host Microbiomes Shape Host–Pathogen Dynamics

   https://doi.org/10.1016/j.pt.2020.04.010  

   Bernardo-Cravo, Adriana P.; Schmeller, Dirk S.; Chatzinotas, Antonis; Vredenburg, Vance T.; Loyau, Adeline (July 2020, Trends in Parasitology)
2. Host Congestion Control

   https://doi.org/10.1145/3603269.3604878  

   Agarwal, Saksham; Krishnamurthy, Arvind; Agarwal, Rachit (September 2023, SIGCOMM)
3. Host species differences in the thermal mismatch of host–parasitoid interactions

   https://doi.org/10.1242/jeb.245702  

   Malinski, Katherine H.; Sorenson, Clyde E.; Moore, M. Elizabeth; Willett, Christopher S.; Kingsolver, Joel G. (June 2023, Journal of Experimental Biology)

   ABSTRACT Extreme high temperatures associated with climate change can affect species directly, and indirectly through temperature-mediated species interactions. In most host–parasitoid systems, parasitization inevitably kills the host, but differences in heat tolerance between host and parasitoid, and between different hosts, may alter their interactions. Here, we explored the effects of extreme high temperatures on the ecological outcomes – including, in some rare cases, escape from the developmental disruption of parasitism – of the parasitoid wasp, Cotesia congregata, and two co-occurring congeneric larval hosts, Manduca sexta and M. quinquemaculata. Both host species had higher thermal tolerance than C. congregata, resulting in a thermal mismatch characterized by parasitoid (but not host) mortality under extreme high temperatures. Despite parasitoid death at high temperatures, hosts typically remain developmentally disrupted from parasitism. However, high temperatures resulted in a partial developmental recovery from parasitism (reaching the wandering stage at the end of host larval development) in some host individuals, with a significantly higher frequency of this partial developmental recovery in M. quinquemaculata than in M. sexta. Hosts species also differed in their growth and development in the absence of parasitoids, with M. quinquemaculata developing faster and larger at high temperatures relative to M. sexta. Our results demonstrate that co-occurring congeneric species, despite shared environments and phylogenetic histories, can vary in their responses to temperature, parasitism and their interaction, resulting in altered ecological outcomes. 

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4. A multi-scale cholera model linking between-host and within-host dynamics

   https://doi.org/10.1142/S1793524518500341  

   Yang, Chayu; Posny, Drew; Bao, Feng; Wang, Jin (April 2018, International Journal of Biomathematics)

   We propose a multi-scale modeling framework to investigate the transmission dynamics of cholera. At the population level, we employ a SIR model for the between-host transmission of the disease. At the individual host level, we describe the evolution of the pathogen within the human body. The between-host and within-host dynamics are connected through an environmental equation that characterizes the growth of the pathogen and its interaction with the hosts outside the human body. We put a special emphasis on the within-host dynamics by making a distinction for each individual host. We conduct both mathematical analysis and numerical simulation for our model in order to explore various scenarios associated with cholera transmission and to better understand the complex, multi-scale disease dynamics. 

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5. Host Controls of Within-Host Disease Dynamics: Insight from an Invertebrate System

   https://doi.org/10.1086/715355  

   Stewart Merrill, Tara E.; Rapti, Zoi; Cáceres, Carla E. (January 2021, The American Naturalist)

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