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Title: Electrochemical sensors for oxidative stress monitoring
Electrochemical sensors are ideally suited for the detection of reactive oxygen and nitrogen species (ROS and RNS) generated during biological processes. This review discusses the latest work in the development of electrochemical microsensors for ROS/RNS and their possible applications for monitoring oxidative stress in biological systems. The performance of recent designs of microelectrodes and electrode materials are discussed along with their functionality in preclinical models of drug efficacy, mitochondrial distress, and endothelial dysfunction. Challenges and opportunities in translating this methodology to study the pathophysiology associated with various diseases are discussed.  more » « less
Award ID(s):
2042544
PAR ID:
10318677
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
Current opinion in electrochemistry
ISSN:
2451-9103
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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