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Title: Participation of S and Se in hydrogen and chalcogen bonds
This article reviews the history and the current state of knowledge concerning the ability of the heavy chalcogen atoms S and Se, and to some extent Te, to participate in a H-bond as either proton donor or acceptor. These atoms are nearly as effective proton acceptors as O, and only slightly weaker as donor. They can also participate in chalcogen bonds where they act as electron acceptors from a nucleophile. These bonds rapidly strengthen as the chalcogen atom becomes larger: S < Se < Te, or if they are surrounded by electron-withdrawing substituents, and can exceed that of many types of H-bonds. Experimental and computational evidence indicates that both H-bonds and chalcogen bonds involving S and Se occur widely in chemical and biological systems, and play an active role in structure and function.  more » « less
Award ID(s):
1954310
PAR ID:
10326169
Author(s) / Creator(s):
Date Published:
Journal Name:
CrystEngComm
Volume:
23
Issue:
39
ISSN:
1466-8033
Page Range / eLocation ID:
6821 to 6837
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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