Pulmonary air leak is the most common complication of lung surgery, with air leaks that persist longer than 5 days representing a major source of post-surgery morbidity. Clinical management of air leaks is challenging due to limited methods to precisely locate and assess leaks. Here, we present a sound-guided methodology that enables rapid quantitative assessment and precise localization of air leaks by analyzing the distinct sounds generated as the air escapes through defective lung tissue. Air leaks often present after lung surgery due to loss of tissue integrity at or near a staple line. Accordingly, we investigated air leak sounds from a focal pleural defect in a rat model and from a staple line failure in a clinically relevant swine model to demonstrate the high sensitivity and translational potential of this approach. In rat and swine models of free-flowing air leak under positive pressure ventilation with intrapleural microphone 1 cm from the lung surface, we identified that: (a) pulmonary air leaks generate sounds that contain distinct harmonic series, (b) acoustic characteristics of air leak sounds can be used to classify leak severity, and (c) precise location of the air leak can be determined with high resolution (within 1 cm) by mappingmore »
SUPERVISED MACHINE LEARNING MODELS FOR LEAK DETECTION IN WATER DISTRIBUTION SYSTEMS
Water distribution systems (WDSs) face a significant challenge in the form of pipe leaks. Pipe leaks can cause loss of a large amount of treated water, leading to pressure loss, increased energy costs, and contamination risks. Locating pipe leaks has been a constant challenge for water utilities and stakeholders due to the underground location of the pipes. Physical methods to detect leaks are expensive, intrusive, and heavily localized. Computational approaches provide an economical alternative to physical methods. Data-driven machine learning-based computational approaches have garnered growing interest in recent years to address the challenge of detecting pipe leaks in WDSs. While several studies have applied machine learning models for leak detection on single pipes and small test networks, their applicability to the real-world WDSs is unclear. Most of these studies simplify the leak characteristics and ignore modeling and measuring device uncertainties, which makes the scalability of their approaches questionable to real-world WDSs. Our study addresses this issue by devising four study cases that account for the realistic leak characteristics (multiple, multi-size, and randomly located leaks) and incorporating noise in the input data to account for the model- and measuring device- related uncertainties. A machine learning-based approach that uses simulated pressure as more »
- Award ID(s):
- 1919228
- Publication Date:
- NSF-PAR ID:
- 10344227
- Journal Name:
- 2nd International Joint Conference on Water Distribution Systems Analysis & Computing and Control in the Water Industry
- Sponsoring Org:
- National Science Foundation
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