IntroductionAI fairness seeks to improve the transparency and explainability of AI systems by ensuring that their outcomes genuinely reflect the best interests of users. Data augmentation, which involves generating synthetic data from existing datasets, has gained significant attention as a solution to data scarcity. In particular, diffusion models have become a powerful technique for generating synthetic data, especially in fields like computer vision. MethodsThis paper explores the potential of diffusion models to generate synthetic tabular data to improve AI fairness. The Tabular Denoising Diffusion Probabilistic Model (Tab-DDPM), a diffusion model adaptable to any tabular dataset and capable of handling various feature types, was utilized with different amounts of generated data for data augmentation. Additionally, reweighting samples from AIF360 was employed to further enhance AI fairness. Five traditional machine learning models—Decision Tree (DT), Gaussian Naive Bayes (GNB), K-Nearest Neighbors (KNN), Logistic Regression (LR), and Random Forest (RF)—were used to validate the proposed approach. Results and discussionExperimental results demonstrate that the synthetic data generated by Tab-DDPM improves fairness in binary classification. 
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                            TADA: phylogenetic augmentation of microbiome samples enhances phenotype classification
                        
                    
    
            Abstract MotivationLearning associations of traits with the microbial composition of a set of samples is a fundamental goal in microbiome studies. Recently, machine learning methods have been explored for this goal, with some promise. However, in comparison to other fields, microbiome data are high-dimensional and not abundant; leading to a high-dimensional low-sample-size under-determined system. Moreover, microbiome data are often unbalanced and biased. Given such training data, machine learning methods often fail to perform a classification task with sufficient accuracy. Lack of signal is especially problematic when classes are represented in an unbalanced way in the training data; with some classes under-represented. The presence of inter-correlations among subsets of observations further compounds these issues. As a result, machine learning methods have had only limited success in predicting many traits from microbiome. Data augmentation consists of building synthetic samples and adding them to the training data and is a technique that has proved helpful for many machine learning tasks. ResultsIn this paper, we propose a new data augmentation technique for classifying phenotypes based on the microbiome. Our algorithm, called TADA, uses available data and a statistical generative model to create new samples augmenting existing ones, addressing issues of low-sample-size. In generating new samples, TADA takes into account phylogenetic relationships between microbial species. On two real datasets, we show that adding these synthetic samples to the training set improves the accuracy of downstream classification, especially when the training data have an unbalanced representation of classes. Availability and implementationTADA is available at https://github.com/tada-alg/TADA. Supplementary informationSupplementary data are available at Bioinformatics online. 
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                            - Award ID(s):
- 1845967
- PAR ID:
- 10425976
- Publisher / Repository:
- Oxford University Press
- Date Published:
- Journal Name:
- Bioinformatics
- Volume:
- 35
- Issue:
- 14
- ISSN:
- 1367-4803
- Format(s):
- Medium: X Size: p. i31-i40
- Size(s):
- p. i31-i40
- Sponsoring Org:
- National Science Foundation
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