In this paper, we propose a new framework to construct confidence sets for a $d$-dimensional unknown sparse parameter ${\boldsymbol \theta }$ under the normal mean model ${\boldsymbol X}\sim N({\boldsymbol \theta },\sigma ^{2}\bf{I})$. A key feature of the proposed confidence set is its capability to account for the sparsity of ${\boldsymbol \theta }$, thus named as sparse confidence set. This is in sharp contrast with the classical methods, such as the Bonferroni confidence intervals and other resampling-based procedures, where the sparsity of ${\boldsymbol \theta }$ is often ignored. Specifically, we require the desired sparse confidence set to satisfy the following two conditions: (i) uniformly over the parameter space, the coverage probability for ${\boldsymbol \theta }$ is above a pre-specified level; (ii) there exists a random subset $S$ of $\{1,...,d\}$ such that $S$ guarantees the pre-specified true negative rate for detecting non-zero $\theta _{j}$’s. To exploit the sparsity of ${\boldsymbol \theta }$, we allow the confidence interval for $\theta _{j}$ to degenerate to a single point 0 for any $j\notin S$. Under this new framework, we first consider whether there exist sparse confidence sets that satisfy the above two conditions. To address this question, we establish a non-asymptotic minimax lower bound for the non-coverage probability over a suitable class of sparse confidence sets. The lower bound deciphers the role of sparsity and minimum signal-to-noise ratio (SNR) in the construction of sparse confidence sets. Furthermore, under suitable conditions on the SNR, a two-stage procedure is proposed to construct a sparse confidence set. To evaluate the optimality, the proposed sparse confidence set is shown to attain a minimax lower bound of some properly defined risk function up to a constant factor. Finally, we develop an adaptive procedure to the unknown sparsity. Numerical studies are conducted to verify the theoretical results.
Varying coefficient models have been used to explore dynamic effects in many scientific areas, such as in medicine, finance, and epidemiology. As most existing models ignore the existence of zero regions, we propose a new soft-thresholded varying coefficient model, where the coefficient functions are piecewise smooth with zero regions. Our new modeling approach enables us to perform variable selection, detect the zero regions of selected variables, obtain point estimates of the varying coefficients with zero regions, and construct a new type of sparse confidence intervals that accommodate zero regions. We prove the asymptotic properties of the estimator, based on which we draw statistical inference. Our simulation study reveals that the proposed sparse confidence intervals achieve the desired coverage probability. We apply the proposed method to analyze a large-scale preoperative opioid study.
more » « less- NSF-PAR ID:
- 10432533
- Publisher / Repository:
- Oxford University Press
- Date Published:
- Journal Name:
- Biometrics
- Volume:
- 79
- Issue:
- 4
- ISSN:
- 0006-341X
- Format(s):
- Medium: X Size: p. 3388-3401
- Size(s):
- ["p. 3388-3401"]
- Sponsoring Org:
- National Science Foundation
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