The sampling and analysis of sewage for pathogens and other biomarkers offers a powerful tool for monitoring and understanding community health trends and potentially predicting disease outbreaks. Since the early months of the COVID-19 pandemic, the use of wastewater-based testing for public health surveillance has increased markedly. However, these efforts have focused on urban and peri-urban areas. In most rural regions of the world, healthcare service access is more limited than in urban areas, and rural public health agencies typically have less disease outcome surveillance data than their urban counterparts. The potential public health benefits of wastewater-based surveillance for rural communities are therefore substantial - though so too are the methodological and ethical challenges. For many rural communities, population dynamics and insufficient, aging, and inadequately maintained wastewater collection and treatment infrastructure present obstacles to the reliable and responsible implementation of wastewater-based surveillance. Practitioner observations and research findings indicate that for many rural systems, typical implementation approaches for wastewater-based surveillance will not yield sufficiently reliable or actionable results. We discuss key challenges and potential strategies to address them. However, to support and expand the implementation of responsible, reliable, and ethical wastewater-based surveillance for rural communities, best practice guidelines and standards are needed.
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Applying data science advances in disease surveillance and control
Applying data science advances in disease surveillance and control Dr. David S. Ebert and Dr. Aaron Wendelboe explain how a cohesive, multidisciplinary, and multi-tiered approach can support a more predictive model in disease surveillance and control. Public health disease surveillance is being conducted in countless settings, including healthcare, vertebrate and invertebrate animals, wastewater, air quality, transportation, and commercial activities, but, attaining the goal of early disease detection has been somewhat elusive. For instance, one of the few key shortcoming of public health preparedness efforts is the insufficient collaboration between multidisciplinary experts, such as data scientists, computer engineers, anthropologists, social scientists, and systems engineers. To address these gaps in knowledge and preparedness, we are responding in a multi-tiered approach with a One Health perspective that will be economically feasible and sustainable. The authors have also engaged a broad set of stakeholders, created broad multidisciplinary teams, are combining relevant data sources in innovative ways that will serve as early indicators, are using advanced technologies for early diagnosis, and advancing analytic methods to maintain high specificity for true event identification.
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- Award ID(s):
- 2200299
- PAR ID:
- 10435533
- Date Published:
- Journal Name:
- Open Access Government
- Volume:
- 39
- Issue:
- 1
- ISSN:
- 2516-3817
- Page Range / eLocation ID:
- 152 to 153
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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A comprehensive approach to integrated one health surveillance and response Surveillance data plays a crucial role in understanding and responding to emerging infectious diseases; here, we learn why adopting a One Health surveillance approach to EIDs can help to protect human, animal, and environmental health. Over 75% of emerging infectious diseases (EIDs) affecting humans are zoonotic diseases with animal hosts, which can be transmitted by waterborne, foodborne, vector-borne, or air-borne pathways. (7) Early detection is important and allows for a rapid response through preventive and control measures. However, early detection of EIDs is hindered by several obstacles, such as climate change, which can alter habitats, leading to shifts in the distribution of disease- carrying vectors like mosquitoes and ticks. This can result in diseases such as malaria, dengue fever, and Lyme disease becoming more common in areas with established transmission or spreading to new areas entirely. (4) Environmental changes such as deforestation and urbanization disrupt ecosystems, increasing the likelihood of zoonotic disease spillover from wildlife to humans. In addition to working at the interface of these changes, detection and tracking of EIDs also requires sharing and standardization of complex data and integrating processes across different regions and health systems.
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The rapidly expanding use of wastewater for public health surveillance requires new strategies to protect privacy rights, while data are collected at increasingly discrete geospatial scales, i.e., city, neighborhood, campus, and building-level. Data collected at high geospatial resolution can inform on labile, short-lived biomarkers, thereby making wastewater-derived data both more actionable and more likely to cause privacy concerns and stigma- tization of subpopulations. Additionally, data sharing restrictions among neighboring cities and communities can complicate efforts to balance public health protections with citizens’ privacy. Here, we have created an encrypted framework that facilitates the sharing of sensitive population health data among entities that lack trust for one another (e.g., between adjacent municipalities with different governance of health monitoring and data sharing). We demonstrate the utility of this approach with two real-world cases. Our results show the feasibility of sharing encrypted data between two municipalities and a laboratory, while performing secure private com- putations for wastewater-based epidemiology (WBE) with high precision, fast speeds, and low data costs. This framework is amenable to other computations used by WBE researchers including population normalized mass loads, fecal indicator normalizations, and quality control measures. The Centers for Disease Control and Pre- vention’s National Wastewater Surveillance System shows ~8 % of the records attributed to collection before the wastewater treatment plant, illustrating an opportunity to further expand currently limited community-level sampling and public health surveillance through security and responsible data-sharing as outlined here.more » « less
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Summary Multi‐compartment models have been playing a central role in modelling infectious disease dynamics since the early 20th century. They are a class of mathematical models widely used for describing the mechanism of an evolving epidemic. Integrated with certain sampling schemes, such mechanistic models can be applied to analyse public health surveillance data, such as assessing the effectiveness of preventive measures (e.g. social distancing and quarantine) and forecasting disease spread patterns. This review begins with a nationwide macromechanistic model and related statistical analyses, including model specification, estimation, inference and prediction. Then, it presents a community‐level micromodel that enables high‐resolution analyses of regional surveillance data to provide current and future risk information useful for local government and residents to make decisions on reopenings of local business and personal travels.
r software and scripts are provided whenever appropriate to illustrate the numerical detail of algorithms and calculations. The coronavirus disease 2019 pandemic surveillance data from the state of Michigan are used for the illustration throughout this paper. -
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Meteorological data for public health surveillance Michael Wimberly, Professor from the University of Oklahoma, walks us through integrating meteorological data for public health surveillance and disease forecasting. Public health surveillance involves the collection, analysis, interpretation, and dissemination of health-related data to plan, implement, and evaluate public health practices. The resulting information supports the detection of emerging health threats, planning interventions, and evaluating policies and programs to protect and improve population health.
- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.56367/OAG-039-10899
