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Abstract Polyvinylpyrrolidone (PVP) fibers embedded with Zinc Oxide nanoparticles (ZnO NPs) were prepared by the centrifugal spinning of aqueous PVP solutions and ZnO NPs. The ZnO NPs were synthesized and coated with either cetyltrimethylammonium bromide or hexadecyltrimethylammonium bromide. The structure and morphology of the nanocomposite fibers were studied using scanning electron microscopy, X‐ray diffraction, energy‐dispersive X‐ray spectroscopy, Fourier transformed infrared spectroscopy and Thermogravimetric analysis. The effect of surfactant coating on the antibacterial activity of ZnO NPs and PVP/ZnO nanocomposite fibers againstEscherichia coli(E. coli) andBacillus megaterium(B. megaterium) bacteria was systematically investigated. The present study indicated that coating the ZnO NPs with surfactants resulted in large and uniform inhibition of bacterial growth.
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Forcespun polyvinylpyrrolidone/copper and polyethylene oxide/copper composite fibers and their use as antibacterial agents
Abstract Copper nanoparticles (CuNPs) embedded in polyvinylpyrrolidone (PVP) and polyethylene oxide (PEO) fiber‐matrices were prepared through centrifugal spinning of PVP/ethanol and PEO/aqueous solutions, respectively. The prime focus of the current study is to investigate the antibacterial activity of composite fibers againstEscherichia coli(E. coli) andBacillus cereus(B. cereus) bacteria. During the fiber formation, the centrifugal spinning parameters such as spinneret rotational speed, spinneret to collector distance, and relative humidity were carefully chosen to obtain long and continuous fibers. The structural and morphological analyses of both composite fibers were investigated using scanning electron microscopy, X‐ray diffraction, energy‐dispersive X‐ray spectroscopy, and thermogravimetric analysis. In the antibacterial test, PVP/Cu and PEO/Cu composite fibrous membranes exhibited inhibition efficiency of 99.98% and 99.99% againstE. coliandB. cereusbacteria, respectively. Basically, CuNPs were well embedded in the fibrous membrane at the nanoscale level, which facilitated the inhibition of bacterial functions through the inactivation of the chemical structure of the cells. Such an effective antibacterial agent obtained from forcespun composite fibers could be promising candidates for biomedical applications.
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- Award ID(s):
- 2122178
- PAR ID:
- 10448127
- Publisher / Repository:
- Wiley Blackwell (John Wiley & Sons)
- Date Published:
- Journal Name:
- Journal of Applied Polymer Science
- Volume:
- 139
- Issue:
- 11
- ISSN:
- 0021-8995
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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