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Title: Interaction of Blood and Bacteria with Slippery Hydrophilic Surfaces
Abstract

Slippery surfaces (i.e., surfaces that display high liquid droplet mobility) are receiving significant attention due to their biofluidic applications. Non‐textured, all‐solid, slippery hydrophilic (SLIC) surfaces are an emerging class of rare and counter‐intuitive surfaces. In this work, the interactions of blood and bacteria with SLIC surfaces are investigated. The SLIC surfaces demonstrate significantly lower platelet and leukocyte adhesion (≈97.2% decrease in surface coverage), and correspondingly low platelet activation, as well as significantly lower bacterial adhesion (≈99.7% decrease in surface coverage of liveEscherichia Coliand ≈99.6% decrease in surface coverage of liveStaphylococcus Aureus) and proliferation compared to untreated silicon substrates, indicating their potential for practical biomedical applications. The study envisions that the SLIC surfaces will pave the path to improved biomedical devices with favorable blood and bacteria interactions.

 
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NSF-PAR ID:
10469376
Author(s) / Creator(s):
 ;  ;  ;  ;  ;  ;  ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
Advanced Materials Interfaces
Volume:
11
Issue:
1
ISSN:
2196-7350
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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