Abstract High taxonomic diversity in non-industrial human gut microbiomes is often interpreted as beneficial; however, it is unclear if taxonomic diversity engenders ecological resilience (i.e. community stability and metabolic continuity). We estimate resilience through genus and species-level richness, phylogenetic diversity, and evenness in short-chain fatty acid (SCFA) production among a global gut metagenome panel of 12 populations (n = 451) representing industrial and non-industrial lifestyles, including novel metagenomic data from Burkina Faso (n = 90). We observe significantly higher genus-level resilience in non-industrial populations, while SCFA production in industrial populations is driven by a few phylogenetically closely related species (belonging toBacteroidesandClostridium), meaning industrial microbiomes have low resilience potential. Additionally, database bias obfuscates resilience estimates, as we were 2–5 times more likely to identify SCFA-encoding species in industrial microbiomes compared to non-industrial. Overall, we find high phylogenetic diversity, richness, and evenness of bacteria encoding SCFAs in non-industrial gut microbiomes, signaling high potential for resilience in SCFA production, despite database biases that limit metagenomic analysis of non-industrial populations.
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A hybrid mechanistic machine learning approach to model industrial network dynamics for sustainable design of emerging carbon capture and utilization technologies
Industrial networks consist of multiple industrial nodes interacting with each other through material exchanges that support the overall production goal of the network.
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- PAR ID:
- 10474299
- Publisher / Repository:
- Royal Society of Chemistry
- Date Published:
- Journal Name:
- Sustainable Energy & Fuels
- Volume:
- 7
- Issue:
- 20
- ISSN:
- 2398-4902
- Page Range / eLocation ID:
- 5129 to 5146
- Subject(s) / Keyword(s):
- Sustainable Networks, Machine Learning
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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