Personalized healthcare (PHC) is a booming sector in the health science domain wherein researchers from diverse technical backgrounds are focusing on the need for remote human health monitoring. PHC employs wearable electronics, viz. group of sensors integrated on a flexible substrate, embedded in the clothes, or attached to the body via adhesive. PHC wearable flexible electronics (FE) offer numerous advantages including being versatile, comfortable, lightweight, flexible, and body conformable. However, finding the appropriate mass manufacturing technologies for these PHC devices is still a challenge. It needs an understanding of the physics, performance, and applications of printing technologies for PHC wearables, ink preparation, and bio-compatible device fabrication. Moreover, the detailed study of the operating principle, ink, and substrate materials of the printing technologies such as inkjet printing will help identify the opportunities and emerging challenges of applying them in manufacturing of PHC wearable devices. In this article, we attempt to bridge this gap by reviewing the printing technologies in the PHC domain, especially inkjet printing in depth. This article presents a brief review of the state-of-the-art wearable devices made by various printing methods and their applications in PHC. It focuses on the evaluation and application of these printing technologies for PHC wearable FE devices, along with advancements in ink preparation and bio-compatible device fabrication. The performance of inkjet, screen, gravure, and flexography printing, as well as the inks and substrates, are comparatively analyzed to aid PHC wearable sensor design, research, fabrication, and mass manufacturing. Moreover, it identifies the application of the emerging mass-customizable printing technologies, such as inkjet printing, in the manufacturing of PHC wearable devices, and reviews the printing principles, drop generation mechanisms, ink formulations, ink-substrate interactions, and matching strategies for printing wearable devices on stretchable substrates. Four surface matching strategies are extracted from literature for the guidance of inkjet printing of PHC stretchable electronics. The electro-mechanical performance of the PHC FE devices printed using four surface matching strategies is comparatively evaluated. Further, the article extends its review by describing the scalable integration of PHC devices and finally presents the future directions of research in printing technologies for PHC wearable devices.
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Fibrous wearable and implantable bioelectronics
Fibrous wearable and implantable devices have emerged as a promising technology, offering a range of new solutions for minimally invasive monitoring of human health. Compared to traditional biomedical devices, fibers offer a possibility for a modular design compatible with large-scale manufacturing and a plethora of advantages including mechanical compliance, breathability, and biocompatibility. The new generation of fibrous biomedical devices can revolutionize easy-to-use and accessible health monitoring systems by serving as building blocks for most common wearables such as fabrics and clothes. Despite significant progress in the fabrication, materials, and application of fibrous biomedical devices, there is still a notable absence of a comprehensive and systematic review on the subject. This review paper provides an overview of recent advancements in the development of fibrous wearable and implantable electronics. We categorized these advancements into three main areas: manufacturing processes, platforms, and applications, outlining their respective merits and limitations. The paper concludes by discussing the outlook and challenges that lie ahead for fiber bioelectronics, providing a holistic view of its current stage of development.
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- Award ID(s):
- 2145802
- PAR ID:
- 10496696
- Publisher / Repository:
- Applied Physics Reviews
- Date Published:
- Journal Name:
- Applied Physics Reviews
- Volume:
- 10
- Issue:
- 3
- ISSN:
- 1931-9401
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract Persistent disparities exist in access to state‐of‐the‐art healthcare disproportionately affecting underserved and vulnerable populations. Advances in wearable sensors enabled by additive manufacturing (AM) offer new opportunities to address such disparities and enhance equitable access advanced diagnostic technologies. Additive manufacturing provides a pathway to rapidly prototype bespoke, multifunctional wearable sensors thereby circumventing existing barriers to innovation for resource‐limited settings imposed by the need for specialized facilities, technical expertise, and capital‐intensive processes. This review examines recent progress in the additive manufacture of wearable platforms for physiological health monitoring. Supported by an initial overview of relevant techniques, representative examples of 3D printed wearable sensors highlight the potential for measuring clinically‐relevant biophysical and biochemical signals of interest. The review concludes with a discussion of the promise and utility of additive manufacturing for wearable sensors, emphasizing opportunities for expanding access to vital healthcare technology and addressing critical health disparities.
- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1063/5.0152744
