One of the fundamental questions in developmental biology is how a cell is specified to differentiate as a specialized cell type. Traditionally, plant cell types were defined based on their function, location, morphology, and lineage. Currently, in the age of single-cell biology, researchers typically attempt to assign plant cells to cell types by clustering them based on their transcriptomes. However, because cells are dynamic entities that progress through the cell cycle and respond to signals, the transcriptome also reflects the state of the cell at a particular moment in time, raising questions about how to define a cell type. We suggest that these complexities and dynamics of cell states are of interest and further consider the roles signaling, stochasticity, cell cycle, and mechanical forces play in plant cell fate specification. Once established, cell identity must also be maintained. With the wealth of single-cell data coming out, the field is poised to elucidate both the complexity and dynamics of cell states.
- Award ID(s):
- 2205141
- PAR ID:
- 10504061
- Publisher / Repository:
- figshare
- Date Published:
- Subject(s) / Keyword(s):
- Soft Condensed Matter
- Format(s):
- Medium: X Size: 634219895 Bytes
- Size(s):
- 634219895 Bytes
- Location:
- Figshare
- Sponsoring Org:
- National Science Foundation
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