skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Title: Mechanical properties of simulated dentin caries treated with metal cations and l-ascorbic acid 2-phosphate
This pH cycling study aimed to investigate the effects of L-Ascorbic acid 2-phosphate (AA2P) salts of Mg, Zn, Mn, Sr, and Ba on the surface microhardness, compressive strength, diametral tensile strength (DTS), and solubility of root canal dentin. 186 cylindrical dentin specimens from 93 teeth were fortified with optimal concentrations of AA2P salts of Mg (0.18 mM), Zn (5.3 µM), Mn (2.2 × 10–8 M), Sr (1.8 µM), and Ba (1.9 µM). Saline was used as the control group. These dentin specimens underwent a 3-day cycling process simulating dentin caries formation through repeated sequences of demineralization and remineralization. Surface microhardness at 100 and 500 µm depths (n = 10/subgroup), scanning electron microscopy (n = 3/group), compressive strength (n = 10/group), DTS (n = 6/group), and solubility (n = 5/group) tests were performed to analyze the dentin specimens. Data were analyzed using Kolmogorov–Smirnov, one-way ANOVA, and Post Hoc Tukey tests (p < 0.05). The control group had significantly lower microhardness at both depths (p < 0.001), reduced DTS (p = 0.001), decreased compressive strength (p < 0.001), and higher weight loss (p < 0.001) than all other groups. The Sr group had the highest compressive strength and microhardness among all the groups. The microhardness was significantly higher for the 500 µm depth than the 100 µm depth (p < 0.001), but the difference in microhardness between depths across groups was not significant (p = 0.211). All fortifying solutions provided some protection against artificial caries lesions. Therefore, these elements might have penetrated and reinforced the demineralized dentin against acid dissolution.  more » « less
Award ID(s):
2312680
PAR ID:
10505613
Author(s) / Creator(s):
; ; ; ; ; ; ;
Publisher / Repository:
Springer Nature
Date Published:
Journal Name:
Odontology
Volume:
112
Issue:
2
ISSN:
1618-1247
Page Range / eLocation ID:
489 to 500
Subject(s) / Keyword(s):
Demineralization Dentin Microhardness pH cycling Remineralization
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. To use planktic foraminiferal tests as paleoproxy substrates, it is necessary to delineate environmental versus biological controls on trace element incorporation. Here we utilize laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to explore interspecies, chamber-to-chamber, and intratest trace element (i.e., Mg, Na, Sr, Ba, Mn, Zn) variability in thickly-calcified specimens of the polar and subpolar planktic foraminifera Neogloboquadrina incompta, N. pachyderma, and Turborotalita quinqueloba collected from plankton tows in the Northern California Current. Among the study taxa, test Mg/Ca, Na/Ca, and Sr/Ca are likely dominantly controlled by depth habitat. The neogloboquadrinids record higher Ba/Ca and Mn/Ca, and also show positive covariance between these elements, possibly due to calcifying in an oxygen-depleted marine snow microhabitat. Trace elements are found to be more enriched in the lamellar calcite than the outer chamber wall dominated by gametogenic crust. The data presented herein provide insight into potential vital effects, paleoproxy considerations, ontogeny, and biomineralization processes. 
    more » « less
  2. A M 2 X 2 compounds that crystallize in the CaAl 2 Si 2 structure type have emerged as a promising class of n- and p-type thermoelectric materials. Alloying on the cation (A) site is a frequently used approach to optimize the thermoelectric transport properties of A M 2 X 2 compounds, and complete solid solubility has been reported for many combinations of cations. In the present study, we investigate the phase stability of the AMg 2 Sb 2 system with mixed occupancy of Mg, Ca, Sr, or Ba on the cation (A) site. We show that the small ionic radius of Mg 2 + leads to limited solubility when alloyed with larger cations such as Sr or Ba. Phase separation observed in such cases indicates a eutectic-like phase diagram. By combining these results with prior alloying studies, we establish an upper limit for cation radius mismatch in A M 2 X 2 alloys to provide general guidance for future alloying and doping studies. 
    more » « less
  3. The solubility values of eight common alloying elements Al, Ca, Ce, Gd, Nd, Sn, Y and Zn in hcp Mg are experimentally measured from diffusion profiles obtained from diffusion multiples and liquid-solid diffusion couples (LSDCs) using electron probe microanalysis. These solubility values are used to establish solidus and solvus lines and compared with the experimental results reported in the literature as well as the computed phase boundaries using two CALPHAD (CALculation of PHAse Diagrams) databases. Our experimental values for Mg-Ca (530, 580, 600, 630 °C), Mg-Ce (605, 630 °C), Mg-Gd (570, 600, 630 °C) and Mg-Nd (615, 630 °C) are the first ever measurements of the hcp solidus for these four binary systems. Additional solubility data obtained from our experiments are reported for Mg-Al (375, 420, 450, 500, 550, 600 °C), Mg-Sn (375, 420, 500, 550, 600 °C), Mg-Y (590, 610, 630 °C), and Mg-Zn (275, 450, 500, 550 °C). Our experimental data are valuable input to future thermodynamic reassessments of the eight binary systems. This study also clearly shows the effectiveness of measuring solidus data using the elegant LSDCs. 
    more » « less
  4. Chronological records of elemental concentrations in fish otoliths are a widely used tool to infer the environmental conditions experienced by individual fish. To interpret elemental signals within the otolith, it is important to understand how both external and internal factors impact ion uptake, transport and incorporation. In this study, we have combined chronological records from otoliths and archival data storage tags to quantify the influence of internal (sex, size, age, growth) and external (temperature, depth, salinity) conditions on otolith elemental chemistry of cod (Gadus morhua) in natural settings of the Baltic Sea. This study focused on elements primarily under physiological control: Phosphorus (P), magnesium (Mg) and zinc (Zn); and elements under environmental control: Strontium (Sr), barium (Ba) and manganese (Mn). Based on known spatial and temporal patterns in environmental conditions and fish size, growth, and maturity, we posed a series of hypotheses of expected otolith element patterns. Partial effects of internal and external drivers on element concentration were analyzed using a Linear Mixed Model approach with random variables (fish and year). Predicted effects of otolith concentrations of all elements under physiological control (P, Mg, Zn) showed similar trends, with distinct seasonal patterns (lowest concentration in late spring, highest concentrations in winter), and a positive correlation with water temperature, in addition to higher Zn and lower P in spawning individuals. Predicted effects of otolith concentrations of elements expected to be predominantly under environmental control showed the predicted geographic and depth-related trends based on ambient salinity (Ba) and coastal hypoxia (Mn). However, contrary to expectation, Sr was unrelated to salinity. Predicted otolith Ba, Sr and Mn concentrations also exhibited pronounced seasonal patterns that were out of phase with each other but appeared to be partly explained by spawning/feeding migrations. While performing laboratory validation studies for adult fish is typically not possible, these results highlight the importance of assessing local water chemistry and freshwater endmembers in one’s study system before otolith elemental chemistry can be reliably used to reconstruct fish habitat use and environmental histories. 
    more » « less
  5. Abstract We present the stellar parameters and chemical abundances of 30 elements for five stars located at large radii (3.5–10.7 times the half-light radius) in the Sextans dwarf spheroidal galaxy. We selected these stars using proper motions, radial velocities, and metallicities, and we confirm them as metal-poor members of Sextans with −3.34 ≤ [Fe/H] ≤ −2.64 using high-resolution optical spectra collected with the Magellan Inamori Kyocera Echelle spectrograph. Four of the five stars exhibit normal abundances of C (−0.34 ≤ [C/Fe] ≤ + 0.36), mild enhancement of theαelements Mg, Si, Ca, and Ti ([α/Fe] = +0.12 ± 0.03), and unremarkable abundances of Na, Al, K, Sc, V, Cr, Mn, Co, Ni, and Zn. We identify three chemical signatures previously unknown among stars in Sextans. One star exhibits large overabundances ([X/Fe] > +1.2) of C, N, O, Na, Mg, Si, and K, and large deficiencies of heavy elements ([Sr/Fe] = −2.37 ± 0.25, [Ba/Fe] = −1.45 ± 0.20, [Eu/Fe] < + 0.05), establishing it as a member of the class of carbon-enhanced metal-poor stars with no enhancement of neutron-capture elements. Three stars exhibit moderate enhancements of Eu (+0.17 ≤ [Eu/Fe] ≤ + 0.70), and the abundance ratios among 12 neutron-capture elements are indicative ofr-process nucleosynthesis. Another star is highly enhanced in Sr relative to heavier elements ([Sr/Ba] = +1.21 ± 0.25). These chemical signatures can all be attributed to massive, low-metallicity stars or their end states. Our results, the first for stars at large radius inSextans, demonstrate that these stars were formed in chemically inhomogeneous regions, such as those found in ultra-faint dwarf galaxies. 
    more » « less