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Title: Dynamic computational phenotyping of human cognition
Computational phenotyping has emerged as a powerful tool for characterizing individual variability across a variety of cognitive domains. An individual’s computational phenotype is defined as a set of mechanistically interpretable parameters obtained from fitting computational models to behavioural data. However, the interpretation of these parameters hinges critically on their psychometric properties, which are rarely studied. To identify the sources governing the temporal variability of the computational phenotype, we carried out a 12-week longitudinal study using a battery of seven tasks that measure aspects of human learning, memory, perception and decision making. To examine the influence of state effects, each week, participants provided reports tracking their mood, habits and daily activities. We developed a dynamic computational phenotyping framework, which allowed us to tease apart the time-varying effects of practice and internal states such as affective valence and arousal. Our results show that many phenotype dimensions covary with practice and affective factors, indicating that what appears to be unreliability may reflect previously unmeasured structure. These results support a fundamentally dynamic understanding of cognitive variability within an individual.  more » « less
Award ID(s):
2024462
PAR ID:
10540130
Author(s) / Creator(s):
; ; ; ;
Publisher / Repository:
Springer Nature
Date Published:
Journal Name:
Nature Human Behaviour
Volume:
8
Issue:
5
ISSN:
2397-3374
Page Range / eLocation ID:
917 to 931
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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