skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Attention:

The NSF Public Access Repository (PAR) system and access will be unavailable from 11:00 PM ET on Friday, May 2 until 12:00 AM ET on Saturday, May 3 due to maintenance. We apologize for the inconvenience.

Explore Research Products in the PAR
It may take a few hours for recently added research products to appear in PAR search results.


Title: Stretchable Nanofiber-Based Felt as a String Electrode for Potential Use in Wearable Glucose Biosensors
Nanofiber technology is leading the revolution of wearable technology and provides a unique capability to fabricate smart textiles. With the novel fabrication technique of electrospinning, nanofibers can be fabricated and then manufactured into a durable conductive string for the application of smart textiles. This paper presents an electrospun nanofiber mesh-based (NF-Felt) string electrode with a conducting polymer coating for an electrochemical enzymatic glucose sensor. The surface area of a nanofiber matrix is a key physical property for enhanced glucose oxidase (GOx) enzyme binding for the development of an electrochemical biosensor. A morphological characterization of the NF-Felt string electrode was performed using scanning electron microscopy (SEM) and compared with a commercially available cotton–polyester (Cot-Pol) string coated with the same conducting polymer. The results from stress–strain testing demonstrated high stretchability of the NF-Felt string. Also, the electrochemical characterization results showed that the NF-Felt string electrode was able to detect a glucose concentration in the range between 0.0 mM and 30.0 mM with a sensitivity of 37.4 μA/mM·g and a detection limit of 3.31 mM. Overall, with better electrochemical performance and incredible flexibility, the NF-Felt-based string electrode is potentially more suitable for designing wearable biosensors for the detection of glucose in sweat.  more » « less
Award ID(s):
1952589 1953089
PAR ID:
10560142
Author(s) / Creator(s):
; ;
Publisher / Repository:
Sensors
Date Published:
Journal Name:
Sensors
Volume:
24
Issue:
4
ISSN:
1424-8220
Page Range / eLocation ID:
1283
Subject(s) / Keyword(s):
electrospun nanofibers flexible string electrodes wearable electronics electrochemical glucose biosensor cyclic voltammetry (CV) electrochemical impedance spectroscopy (EIS)
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. ; ; (, Journal of Materials Chemistry B)
    Uniform and porous CoNi 2 Se 4 was successfully synthesized by electrodeposition onto a composite electrode comprising reduced graphene oxide (rGO) anchored on a Ni foam substrate (prepared hydrothermally). This CoNi 2 Se 4 –rGO@NF composite electrode has been employed as an electrocatalyst for the direct oxidation of glucose, thereby acting as a high-performance non-enzymatic glucose sensor. Direct electrochemical measurement with the as-prepared electrode in 0.1 M NaOH revealed that the CoNi 2 Se 4 –rGO nanocomposite has excellent electrocatalytic activity towards glucose oxidation in an alkaline medium with a sensitivity of 18.89 mA mM −1 cm −2 and a wide linear response from 1 μM to 4.0 mM at a low applied potential of +0.35 V vs. Ag|AgCl. This study also highlights the effect of decreasing the anion electronegativity on enhancing the electrocatalytic efficiency by lowering the potential needed for glucose oxidation. The catalyst composite also exhibits high selectivity towards glucose oxidation in the presence of several interferents normally found in physiological blood samples. A low glucose detection limit of 0.65 μM and long-term stability along with a short response time of approximately 4 seconds highlights the promising performance of the CoNi 2 Se 4 –rGO@NF electrode for non-enzymatic glucose sensing with high precision and reliability. 
    more » « less
  2. ; ; ; ; (, Electronic Materials)
    A triboelectric nanogenerator (TENG) is one of the most significantly innovative microdevices for built-in energy harvesting with wearable and portable electronics. In this study, the forcespinning technology was used to synthesize a nanofiber (NF) mat-based TENG. Polyvinylidene fluoride (PVDF) membrane was used as the negative triboelectric electrode/pole, and chemically designed and functionalized thermoplastic polyurethane (TPU) was used as the positive electrode/pole for the TENG. The electronic interference, sensitivity, and gate voltage of the synthesized microdevices were investigated using chemically modified bridging of multi-walled carbon nanotubes (MWCNT) with a TPU polymer repeating unit and bare TPU-based positive electrodes. The chemical functionality of TPU NF was integrated during the NF preparation step. The morphological features and the chemical structure of the nanofibers were characterized using a field emission scanning electron microscope and Fourier-transform infrared spectroscopy. The electrical output of the fabricated MWCNT-TPU/PVDF TENG yielded a maximum of 212 V in open circuit and 70 µA in short circuit at 240 beats per minute, which proved to be 79% and 15% higher than the TPU/PDVF triboelectric nanogenerator with an electronic contact area of 3.8 × 3.8 cm2, which indicates that MWCNT enhanced the electron transportation facility, which results in significantly enhanced performance of the TENG. This device was further tested for its charging capacity and sensory performance by taking data from different body parts, e.g., the chest, arms, feet, hands, etc. These results show an impending prospect and versatility of the chemically functionalized materials for next-generation applications in sensing and everyday energy harvesting technology. 
    more » « less
  3. ; ; (, 2021 IEEE Sensors)
    A glucose biofuel cell on a flexible bacterial nanocellulose film was prepared. The bioelectrodes were printed using gold ink as the conductive material. The anode was modified with colloidal platinum for the oxidation of glucose. The cathode was modified with a nanocomposite comprising gold nanoparticles (AuNPs) and silver oxide (Ag2O) nanoparticles. The cathode was characterized via cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and UV spectroscopy techniques. The assembled biofuel cell generated a maximum open circuit voltage (V oc ) of 0.485 V, short circuit current (I sc ) of 0.352 mA/cm 2 , and a maximum peak power density (P max ) of 0.032 mW/cm 2 when operating in 30 mM concentration. This system showed a stable and linear performance with a linear range of 1 mM to 30 mM glucose. The gold printed electrode process is applicable to the development of wearable and implantable abiotic biofuel cell. 
    more » « less
  4. ; ; (, ChemistrySelect)
    Abstract A simple and environmentally‐friendly approach was developed to synthesize 2D CuO nanosheets using electrochemical deposition. The formed 2D CuO nanosheets (NSs) exhibit numerous advantageous properties such as no toxicity, high electrical conductivity, large active surface area, and a p‐type semiconducting nature with a band gap of 1.2 eV. A sensitive electrochemical sensor was constructed for the amperometric detection of glucose to take advantage of these characteristics. The fabricated sensor displayed an excellent sensitivity of 2710 μA mM−1 cm−2along with a wide linear range of 0.001–1.0 mM and a lower limit of detection of 0.8 μM (S/N=3). Additionally, the modified electrode possesses high selectivity and good stability. The outstanding electrocatalytic performance of the electrode is attributed to a large active surface area, unique structural morphology, and the high conductivity of the 2D CuO nanosheets. 
    more » « less
  5. ; ; (, SLAS TECHNOLOGY: Translating Life Sciences Innovation)
    A novel electrochemical glucose sensor was created for a simple but semiquantitative visual screening of specific glucose concentrations in urine. This noninvasive glucose biosensor integrated a disposable, paper-based sensing strip and a simple amplifier circuit with a visual readout. The paper strip consisted of five enzyme-activated electrodes. Each electrode was connected to a specific indicator circuit that triggered a light-emitting diode (LED) when a predefined glucose concentration was reached. The device features (1) low-cost, disposable, paper-based glucose oxidase (GOx)/poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) sensing electrodes, (2) simple signal amplification, and (3) on-site, rapid, and visual detection. The sensor generated reliable, discrete visual responses to determine five glucose levels (1, 2, 3, 4, and higher than 4 mM) in urine in less than 2 min. This innovative approach will provide a simple but powerful glucose sensing paradigm for use in POC diagnostics. 
    more » « less
  • Citation Formats
  • MLA
  • APA
  • Chicago
  • BibTeX
  • Save / Share this Record
  • Send to Email