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Electrotactile stimulus is a form of sensory substitution in which an electrical signal is perceived as a mechanical sensation. The electrotactile effect could, in principle, recapitulate a range of tactile experience by selective activation of nerve endings. However, the method has been plagued by inconsistency, galvanic reactions, pain and desensitization, and unwanted stimulation of nontactile nerves. Here, we describe how a soft conductive block copolymer, a stretchable layout, and concentric electrodes, along with psychophysical thresholding, can circumvent these shortcomings. These purpose-designed materials, device layouts, and calibration techniques make it possible to generate accurate and reproducible sensations across a cohort of 10 human participants and to do so at ultralow currents (≥6 microamperes) without pain or desensitization. This material, form factor, and psychophysical approach could be useful for haptic devices and as a tool for activation of the peripheral nervous system.more » « less
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Abstract The generation of pressure perturbations in matter stimulated by pulsed light is a method widely recognized as the photoacoustic or light‐induced thermoelastic effect. In a series of psychophysical experiments, the robustness of the tactile perception generated with a variety of light sources is examined: a diverging pulsed laser used for photoacoustic tomography optical parameter oscillation (OPO), a miniature diode laser (MDL), and a commercial digital light processing (DLP) projector. It is demonstrated that participants can accurately detect, categorically describe the sensations, and discern the direction of pulsed light travel. High detection accuracy is reported as follows: (d′ = 4.95 (OPO);d′ = 2.78 (modulated MDL);d′ = 2.99 (DLP)) of the stimulus on glabrous skin coated with a thin layer of dye absorber. For all light sources, the predominant sensation is felt as vibration at the distal phalanx (i.e., fingertip, 55.21–57.29%) and the proximal phalanx (41.67–44.79%). At the fingertip, thermal sensations are perceived less frequently than mechanical ones. Moreover, these haptic effects are preserved under a wide range of pulse widths, spot sizes, optical energies, and wavelengths of the light sources. This form of sensory stimulation demonstrates a generalizable non‐contact, non‐optogenetic, in situ activation of the mechanosensory system.more » « less
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Abstract In this work, a portable venturi tube capable of measuring bidirectional respiratory flow is developed and correlated the measurements to pulmonary function. Pressure signals are transduced using flexible and compressible capacitive foam sensors embedded into the wall of the device. In this configuration, the sensors are able to provide differential pressure readings, from which the airflow rate passing through the tube could be extrapolated. Utilizing the venturi effect, the geometry of the spirometer tube is designed through finite element analysis to measure respiratory airflow during inhalation and exhalation. The device tube is 3D‐printed and used to measure tidal breathing and deep breathing, along with peak expiratory flow rates, on a healthy individual. This spirometer design allows for easy‐to‐use point‐of‐care diagnoses and has the potential to improve the care of respiratory illnesses.more » « less
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Abstract In light of the significant damage observed after earthquakes in Japan and New Zealand, enhanced performing seismic force‐resisting systems and energy dissipation devices are increasingly being utilized in buildings. Numerical models are needed to estimate the seismic response of these systems for seismic design or assessment. While there have been studies on modeling uncertainty, selecting the model features most important to response can remain ambiguous, especially if the structure employs less well‐established lateral force‐resisting systems and components. Herein, a global sensitivity analysis was used to address modeling uncertainty in specimens with elastic spines and force‐limiting connections (FLCs) physically tested at full‐scale at the E‐Defense shake table in Japan. Modeling uncertainty was addressed for both model class and model parameter uncertainty by varying primary models to develop several secondary models according to pre‐established uncertainty groups. Numerical estimates of peak story drift ratio and floor acceleration were compared to the results from the experimental testing program using confidence intervals and root‐mean‐square error. Metrics such as the coefficient of variation, variance, linear Pearson correlation coefficient, and Sobol index were used to gain intuition about each model feature's contribution to the dispersion in estimates of the engineering demands. Peak floor acceleration was found to be more sensitive to modeling uncertainty compared to story drift ratio. Assumptions for the spine‐to‐frame connection significantly impacted estimates of peak floor accelerations, which could influence future design methods for spines and FLC in enhanced lateral‐force resisting systems.more » « less
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Abstract Durable and conductive interfaces that enable chronic and high‐resolution recording of neural activity are essential for understanding and treating neurodegenerative disorders. These chronic implants require long‐term stability and small contact areas. Consequently, they are often coated with a blend of conductive polymers and are crosslinked to enhance durability despite the potentially deleterious effect of crosslinking on the mechanical and electrical properties. Here the grafting of the poly(3,4 ethylenedioxythiophene) scaffold, poly(styrenesulfonate)‐b‐poly(poly(ethylene glycol) methyl ether methacrylate block copolymer brush to gold, in a controlled and tunable manner, by surface‐initiated atom‐transfer radical polymerization (SI‐ATRP) is described. This “block‐brush” provides high volumetric capacitance (120 F cm─3), strong adhesion to the metal (4 h ultrasonication), improved surface hydrophilicity, and stability against 10 000 charge–discharge voltage sweeps on a multiarray neural electrode. In addition, the block‐brush film showed 33% improved stability against current pulsing. This approach can open numerous avenues for exploring specialized polymer brushes for bioelectronics research and application.more » « less