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Free, publicly-accessible full text available May 22, 2023
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Free, publicly-accessible full text available December 1, 2022
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Free, publicly-accessible full text available August 18, 2022
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Free, publicly-accessible full text available October 1, 2022
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Abstract The use of graph theory models is widespread in biological pathway analyses as it is often desired to evaluate the position of genes and proteins in their interaction networks of the biological systems. In this article, we argue that the common standard graph centrality measures do not sufficiently capture the informative topological organizations of the pathways, and thus, limit the biological inference. While key pathway elements may appear both upstream and downstream in pathways, standard directed graph centralities attribute significant topological importance to the upstream elements and evaluate the downstream elements as having no importance.We present a directed graphmore »
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Early programming courses, such as CS1, are an important time to capture the interest of the students while imparting important technical knowledge. Yet many CS1 sections use contrived assignments and activities that tend to make students uninterested and doubt the usefulness of the content. We demonstrate that one can make an interesting CS1 experience for students by coupling interesting datasets with visual representations and interactive applications. Our approach enables teaching an engaging early programming course without changing the content of that course. This approach relies on the BRIDGES system that has been under development for the past 5 years; BRIDGESmore »
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This workshop provides instructors with a hands-on introduction to BRIDGES, a software infrastructure for programming assignments in early computer science courses, including introductory programming (CS1, CS2), data structures, and algorithm analysis. BRIDGES provides capabilities for creating more engaging programming assignments, including: (1) a simplified API for accessing real-world data sets, including from social networks; scientific, government, and civic organizations; and movie, music, and literature collections; (2) interesting visualizations of the data, (3) an easy to use API that supports creation of games that leverage real-world data, and, (4) algorithm benchmarking. Workshop attendees will engage in hands-on experience with BRIDGES withmore »
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Computer Science students in algorithm courses often drop out and feel that what they are learning is disconnected from real life programming. Instructors, on the other hand, feel that algorithmic content is foundational for the long term development of students. The disconnect seems to stem from students not perceiving the importance of algorithmic paradigms, and how they impact performance in applications. We present the point of view that by solving real-world problems where algorithmic paradigms and complexity matter, students will become more engaged with the course and appreciate its importance. Our approach relies on a lean educational framework that providesmore »