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  1. Healthcare capacity shortage contributes to poor access in many countries. Moreover, rapid urbanization often occurring in these countries has exacerbated the imbalance between healthcare capacity and need. One way to address the above challenge is expanding the total capacity and redistributing the capacity spatially. In this research, we studied the problem of locating new hospitals in a two-tier outpatient care system comprising multiple central and district hospitals, and upgrading existing district hospitals to central hospitals. We formulated the problem with a discrete location optimization model. To parameterize the optimization model, we used a multinomial logit model to characterize individual patients’ diverse hospital choice and to quantify the patient arrival rates at each hospital accordingly. To solve the hard nonlinear combinatorial optimization problem, we developed a queueing network model to approximate the impact of hospital locations on patient flows. We then proposed a multi-fidelity optimization approach, which involves both the aforementioned queuing network model as a surrogate and a self-developed stochastic simulation as the high-fidelity model. With a real-world case study of Shanghai, we demonstrated the changes in the care network and examined the impacts on the network design by population center emergence, governmental budget change and considering patients with different age groups or income levels. Note to Practitioners —Our work focuses on improving system-wide care access in a two-tier care network. We believe that our work can lead to effective development of a location analytics tool for city-wide healthcare system planners. We also think the importance of this study is further strengthened by the case studies based on real-world hospital choice experimental data from Shanghai, China, a region suffering from the imbalance between healthcare capacity and need. Our case studies are expected to make recommendations on care facility expansion and dispersion to better align with the spatial distribution of residential communities and patient hospital choice behavior. 
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  2. While prior studies have designed incentive mechanisms to attract the public to share their collected data, they tend to ignore information asymmetry between data requesters and collectors. In reality, the sensing costs information (time cost, battery drainage, bandwidth occupation of mobile devices, and so on) is the private information of collectors, which is unknown by the data requester. In this article, we model the strategic interactions between health-data requester and collectors using a bilevel optimization model. Considering that the crowdsensing market is open and the participants are equal, we propose a Walrasian equilibrium-based pricing mechanism to coordinate the interest conflicts between health-data requesters and collectors. Specifically, based on the exchange economic theory, we transform the bilevel optimization problem into a social welfare maximization problem with the constraint condition that the balance between supply and demand, and dual decomposition is then employed to divide the social welfare maximization problem into a set of subproblems that can be solved by health-data requesters and collectors. We prove that the optimal task price is equal to the marginal utility generated by the collector's health data. To avoid obtaining the collector's private information, a distributed iterative algorithm is then designed to obtain the optimal task pricing strategy. Furthermore, we conduct computational experiments to evaluate the performance of the proposed pricing mechanism and analyze the effects of intrinsic rewards, sensing costs on optimal task prices, and collectors' health-data supplies. 
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  3. Opioid overdose rescue is very time-sensitive. Hence, drone-delivered naloxone has the potential to be a transformative innovation due to its easily deployable and flexible nature. We formulate a Markov Decision Process (MDP) model to dispatch the appropriate drone after an overdose request arrives and to relocate the drone to its next waiting location after having completed its current task. Since the underlying optimization problem is subject to the curse of dimensionality, we solve it using ad-hoc state aggregation and evaluate it through a simulation with higher granularity. Our simulation-based comparative study is based on emergency medical service data from the state of Indiana. We compare the optimal policy resulting from the scaled-down MDP model with a myopic policy as the baseline. We consider the impact of drone type and service area type on outcomes, which offers insights into the performance of the MDP suboptimal policy under various settings. 
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  4. Emergency medical service must be time sensitive. However, in many cases, satisfactory service cannot be ensured due to inconvenient logistics. For its easily deployable and widely accessible nature, unmanned aerial vehicles (UAVs) have the potential to improve the service, especially in areas that are traditionally under-served. In this paper, we develop a service network optimization problem for locating UAV bases, staffing a UAV fleet at each constructed base, and zoning demand nodes. We formulate a location-allocation optimization model with numerically simulated waiting times for the service zones as the objective. We adapt a genetic algorithm to solve the optimization model. We test our network optimization approach on instances of traumatic injury cases. By comparing our approach to a two-phase method in Boutilier et al. [1], we suggest an up to 60% reduction in mean waiting time. 
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  5. Trauma continues to be the leading cause of mortality and morbidity among US citizens aged <44 years. Literature suggests that geographical maldistribution of trauma centers (TCs) is associated with increasing fatality rate. Existing models for TC network design do not address the question often raised by trauma decision makers: how many TCs are required to achieve acceptable levels of mistriages? We propose a model to optimize the network of TCs under mistriage constraints. We propose a notional field triage protocol to estimate mistriages (under and over), based on existing guidelines in the trauma literature. Due to the complexity of the underlying model, we propose a Particle Swarm Optimization based solution approach. We use 2012 data from the State of Ohio, and model both ground and air transportation modes. Our results show that, for 2012 mistriage levels, it is possible to reduce the number of TCs from 21 to 10 by distributing them appropriately across urban and rural areas. Further, redistributing these 21 TCs can help satisfy the recommendation of under-triage ≤0.05 by the American College of Surgeons. In general, our study provides trauma decision makers an ability to determine a network that could improve care and/or reduce cost. 
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