skip to main content


Search for: All records

Award ID contains: 2036134

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Oraevsky, Alexander A. ; Wang, Lihong V. (Ed.)
  2. This Letter reports the integration of microlenses (MLs) on a surface-micromachined optical ultrasound transducer (SMOUT) array to enable parallel ultrasound data readout from a multiplicity of elements. The MLs are fabricated by photoresist patterning and reflow, and their focal lengths are optimized with parametric studies. Experiments are conducted to characterize the acoustic responsivity and its uniformity of the SMOUT-ML elements under different conditions. The temporal stability of SMOUT-ML elements immersed in water is assessed by monitoring their acoustic response continuously for 1 week. Parallel ultrasound signal readout is simulated with a small group of SMOUT-ML elements. Experimental results show that high acoustic sensitivity and excellent long-term stability can be achieved by the ML-integrated SMOUT array, which could provide a promising approach for enabling parallel ultrasound data acquisition for improving the imaging speed of 3D acoustic tomography.

     
    more » « less
  3. This Letter reports a new, to the best of our knowledge, photoacoustic excitation method for evaluating the shear viscoelastic properties of soft tissues. By illuminating the target surface with an annular pulsed laser beam, circularly converging surface acoustic waves (SAWs) are generated, focused, and detected at the center of the annular beam. The shear elasticity and shear viscosity of the target are extracted from the dispersive phase velocity of the SAWs based on the Kelvin–Voigt model and nonlinear regression fitting. Agar phantoms with different concentrations, and animal liver and fat tissue samples have successfully been characterized. Different from previous methods, the self-focusing of the converging SAWs allows sufficient SNR to be obtained even with low pulsed laser energy density, which makes this approach well compatible with soft tissues under bothex vivoandin vivotesting conditions.

     
    more » « less
  4. Oraevsky, Alexander A. ; Wang, Lihong V. (Ed.)
  5. Piyawattanametha, Wibool ; Park, Yong-Hwa ; Zappe, Hans (Ed.)
  6. This Letter reports acoustic-resolution-photoacoustic microscopy (AR-PAM) based on a new optically transparent focused polyvinylidene fluoride (PVDF) transducer with a high acoustic numerical aperture (NA) of 0.64. Owing to the improved fabrication process, the new transducer has a much higher NA (0.64) than the previously reported low-NA transducer (NA=0.23). The acoustic center frequency and (pulse-echo) bandwidth are also increased to 36 and 44 MHz, respectively, which provides a 38 µm acoustic focal spot size and 210 µm acoustic depth of focus. For demonstration, AR-PAM was conducted on a twisted wire target in water and chicken breast tissue, andin vivoon a mouse tail. The imaging results show that high acoustic resolution and sensitivity can be achieved with a simple and compact setup to resolve the target at different depths. Such capabilities can be useful for the development of new AR-PAM systems for handheld, wearable, and even endoscopic imaging applications.

     
    more » « less