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Award ID contains: 2238812

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  1. ; ; ; ; ; ; ; ; ; ; et al (, Journal of Materials Chemistry B)
    A novel drug delivery system hitchhiking albumin as a drug carrier with tuneable redox-responsive drug release. 
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    Full Text Available 
  2. ; ; ; ; ; ; ; ; ; ; et al (, ACS Applied Materials & Interfaces)
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  3. ; ; ; ; ; ; (, Macromolecules)
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  4. ; ; ; ; ; (, Nanoscale)
    Messenger RNA (mRNA)-based therapeutic agents have demonstrated significant potential in recent times, particularly in the context of the COVID-19 pandemic outbreak. As a promising prophylactic and therapeutic strategy, polypeptide-based mRNA... 
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  5. (, Prof Rajeev Prabhakar)
    Rajeev Prabhakar (Ed.)
    Cyclic carbonate is an important intermediate for preparing polycarbonates, which are crucial materials in diverse research fields. This study introduced a three-step approach to synthesizing a disulfide-containing cyclic carbonate monomer, with confirmation through proton nuclear magnetic resonances (1H NMR) and high-resolution mass spectrum analysis. The resulting monomer holds the potential for subsequent synthesis of responsive functional aliphatic polycarbonates, providing promise for advanced biomedical applications. 
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    Accepted Manuscript Full Text Available
  6. ; ; ; ; (, Nano TransMed)
    Ye, Qingsong (Ed.)
    Biodegradable and adaptable polymeric materials are currently being studied due to their wide scope of potential applications, from nanomedicine to novel multifunctional materials. One such class of polymers are poly(disulfide)s, which contain repeating disulfide bonds in their main chain. Lipoic acid, or thioctic acid, is a biologically derived small molecule containing a 1,2-dithiolane ring capable of undergoing ring opening polymerization to yield poly(disulfide)s. In this review, we highlight the synthesis of lipoic acid-based poly(disulfide)s through thermal and thiolate-initiated ring opening polymerizations, and the development of methodology pertaining to the synthetic methods. We further discuss the biomedical applications of poly(disulfide)s, which have been widely used to construct various responsive biomaterials, including polymer-drug conjugates, nanoparticles, hydrogels, and adhesives. 
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