The emergence of electrowetting-on-dielectric (EWOD) in the early 2000s made the once-obscure electrowetting phenomenon practical and led to numerous activities over the last two decades. As an eloquent microscale liquid handling technology that gave birth to digital microfluidics, EWOD has served as the basis for many commercial products over two major application areas: optical, such as liquid lenses and reflective displays, and biomedical, such as DNA library preparation and molecular diagnostics. A number of research or start-up companies ( e.g. , Phillips Research, Varioptic, Liquavista, and Advanced Liquid Logic) led the early commercialization efforts and eventually attracted major companies from various industry sectors ( e.g. , Corning, Amazon, and Illumina). Although not all of the pioneering products became an instant success, the persistent growth of liquid lenses and the recent FDA approvals of biomedical analyzers proved that EWOD is a powerful tool that deserves a wider recognition and more aggressive exploration. This review presents the history around major EWOD products that hit the market to show their winding paths to commercialization and summarizes the current state of product development to peek into the future. In providing the readers with a big picture of commercializing EWOD and digital microfluidics technology, our goal is to inspire further research exploration and new entrepreneurial adventures.
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Enhancing the Response Time of Electrowetting Lenses Using Voltage Shaping
We have demonstrated tunability of the response time of electrowetting lenses from underdamped to overdamped through input voltage shaping. This strategy shows great promise to further optimize the response time of electrowetting lenses.
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- NSF-PAR ID:
- 10033101
- Date Published:
- Journal Name:
- Conference on Lasers and ElectroOptics
- Page Range / eLocation ID:
- SM4C.7
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract Atmospheric rivers (ARs) result in precipitation over land and ocean. Rainfall on the ocean can generate a buoyant layer of freshwater that impacts exchanges between the surface and the mixed layer. These “fresh lenses” are important for weather and climate because they may impact the ocean stratification at all time scales. Here we use in situ ocean data, collocated with AR events, and a one-dimensional configuration of a general circulation model, to investigate the impact of AR precipitation on surface ocean salinity in the California Current System (CCS) on seasonal and event-based time scales. We find that at coastal and onshore locations the CCS freshens through the rainy season due to AR events, and years with higher AR activity are associated with a stronger freshening signal. On shorter time scales, model simulations suggest that events characteristic of CCS ARs can produce salinity changes that are detectable by ocean instruments (≥0.01 psu). Here, the surface salinity change depends linearly on rain rate and inversely on wind speed. Higher wind speeds ( U > 8 m s −1 ) induce mixing, distributing freshwater inputs to depths greater than 20 m. Lower wind speeds ( U ≤ 8 m s −1 ) allow freshwater lenses to remain at the surface. Results suggest that local precipitation is important in setting the freshwater seasonal cycle of the CCS and that the formation of freshwater lenses should be considered for identifying impacts of atmospheric variability on the upper ocean in the CCS on weather event time scales. Significance Statement Atmospheric rivers produce large amounts of rainfall. The purpose of this study is to understand how this rain impacts the surface ocean in the California Current System on seasonal and event time scales. Our results show that a greater precipitation over the rainy season leads to a larger decrease in salinity over time. On shorter time scales, these atmospheric river precipitation events commonly produce a surface salinity response that is detectable by ocean instruments. This salinity response depends on the amount of rainfall and the wind speed. In general, higher wind speeds will cause the freshwater input from rain to mix deeper, while lower wind speeds will have reduced mixing, allowing a layer of freshwater to persist at the surface.more » « less
- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Conference Paper:
- https://doi.org/10.1364/CLEO_SI.2017.SM4C.7
