Recent efforts in deploying Deep Neural Networks for object detection in real world applications, such as autonomous driving, assume that all relevant object classes have been observed during training. Quantifying the performance of these models in settings when the test data is not represented in the training set has mostly focused on pixel-level uncertainty estimation techniques of models trained for semantic segmentation. This paper proposes to exploit additional predictions of semantic segmentation models and quantifying its confidences, followed by classification of object hypotheses as known vs. unknown, out of distribution objects. We use object proposals generated by Region Proposal Network (RPN) and adapt distance aware uncertainty estimation of semantic segmentation using Radial Basis Functions Networks (RBFN) for class agnostic object mask prediction. The augmented object proposals are then used to train a classifier for known vs. unknown objects categories. Experimental results demonstrate that the proposed method achieves parallel performance to state of the art methods for unknown object detection and can also be used effectively for reducing object detectors' false positive rate. Our method is well suited for applications where prediction of non-object background categories obtained by semantic segmentation is reliable.
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DOMINO: Domain-Aware Model Calibration in Medical Image Segmentation
Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern deep neural networks are poorly calibrated, compromising trustworthiness and reliability. Medical image segmentation particularly suffers from this due to the natural uncertainty of tissue boundaries. This is exasperated by their loss functions, which favor overconfidence in the majority classes. We address these challenges with DOMINO, a domain-aware model calibration method that leverages the semantic confusability and hierarchical similarity between class labels. Our experiments demonstrate that our DOMINO-calibrated deep neural networks outperform non-calibrated models and state-of-the-art morphometric methods in head image segmentation. Our results show that our method can consistently achieve better calibration, higher accuracy, and faster inference times than these methods, especially on rarer classes. This performance is attributed to our domain-aware regularization to inform semantic model calibration. These findings show the importance of semantic ties between class labels in building confidence in deep learning models. The framework has the potential to improve the trustworthiness and reliability of generic medical image segmentation models. The code for this article is available at: https://github.com/lab-smile/DOMINO.
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- Award ID(s):
- 1908299
- NSF-PAR ID:
- 10358376
- Editor(s):
- Wang, L.; Dou, Q.; Fletcher, P.T.; Speidel, S.; Li, S.
- Date Published:
- Journal Name:
- Medical Image Computing and Computer Assisted Intervention – MICCAI 2022
- Volume:
- 13435
- Page Range / eLocation ID:
- 454-463
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Conference Paper:
- https://doi.org/10.1007/978-3-031-16443-9_44
