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Abstract Foldit is a citizen science video game in which players tackle a variety of complex biochemistry puzzles. Here, we describe a new series of puzzles in which Foldit players improve the accuracy of the public repository of experimental protein structure models, the Protein Data Bank (PDB). Analyzing the results of these puzzles showed that the Foldit players were able to considerably improve the deposited structures and thus, in most cases, improved the output of the automated PDB-REDO refinement pipeline. These improved structures are now being hosted at PDB-REDO. These efforts highlight the continued need for the engagement of the lay population in science.
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Community formation in wealth-mediated thermodynamic strategy evolution
We study a dynamical system defined by a repeated game on a 1D lattice, in which the players keep track of their gross payoffs over time in a bank. Strategy updates are governed by a Boltzmann distribution, which depends on the neighborhood bank values associated with each strategy, relative to a temperature scale, which defines the random fluctuations. Players with higher bank values are, thus, less likely to change strategy than players with a lower bank value. For a parameterized rock–paper–scissors game, we derive a condition under which communities of a given strategy form with either fixed or drifting boundaries. We show the effect of a temperature increase on the underlying system and identify surprising properties of this model through numerical simulations.
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- Award ID(s):
- 1814876
- PAR ID:
- 10363854
- Date Published:
- Journal Name:
- Chaos: An Interdisciplinary Journal of Nonlinear Science
- Volume:
- 32
- Issue:
- 10
- ISSN:
- 1054-1500
- Page Range / eLocation ID:
- 103103
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1063/5.0105969
