The COVID-19 pandemic has accelerated the shift from traditional in-person teaching to remote and online learning, necessitating a more adaptable educational platform to serve the diverse needs of students. Transforming hands-on “wet lab” activities into virtual “dry lab” exercises can promote a more accessible and flexible learning environment, offering innovative methods to improve online teaching outcomes, incorporate interactive components, and provide student support. Here we describe our effort of utilizing NUPACK, a free cloud-based web application, to develop new educational modules on nucleic acids for teaching biochemistry lectures and laboratories. These modules include fundamental topics such as melting temperature, hybridization equilibrium, free energy, secondary folding structures of nucleic acids, and the thermal stability of single-nucleotide polymorphisms. The NUPACK-based DNA computational lab not only provides a hands-on learning experience to enhance students’ understanding of nucleic acid structures, hybridizations, and characteristics but also facilitated the transition to remote learning during the pandemic. Furthermore, these computation-assisted DNA experiments have been extended to engage local high school students at Rutgers UniversityCamden. This article summarizes the curriculum development and guidelines for the DNA computational lab, aiming to benefit the education of nucleic acids in biochemistry for a wider audience of educators and learners. 
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                            On-Campus Field Experiences Help Students to Learn and Enjoy Water Science During the COVID-19 Pandemic
                        
                    
    
            Online modes of teaching and learning have gained increased attention following the COVID-19 pandemic, resulting in education delivery trends likely to continue for the foreseeable future. It is therefore critical to understand the implications for student learning outcomes and their interest in or affinity towards the subject, particularly in water science classes, where educators have traditionally employed hands-on outdoor activities that are difficult to replicate online. In this study, we share our experiences adapting a field-based laboratory activity on groundwater to accommodate more than 700 students in our largest-enrollment general education course during the pandemic. As part of our adaptation strategy, we offered two versions of the same exercise, one in-person at the Mirror Lake Water Science Learning Laboratory, located on Ohio State University’s main campus, and one online. Although outdoor lab facilities have been used by universities since at least the 1970s, this research is novel in that 1) it considers not only student achievement but also affinity for the subject, 2) it is the first of its kind on The Ohio State University’s main campus, and 3) it was conducted during the COVID-19 pandemic, at a time when most university classes were unable to take traditional field trips. We used laboratory grades and a survey to assess differences in student learning and affinity outcomes for in-person and online exercises. Students who completed the in-person exercise earned better scores than their online peers. For example, in Fall 2021, the median lab score for the in-person group was 97.8%, compared to 91.7% for the online group. The in-person group also reported a significant ( p < 0.05) increase in how much they enjoyed learning about water, while online students reported a significant decrease. Online students also reported a significant decrease in how likely they would be to take another class in water or earth sciences. It is unclear whether the in-person exercise had better learning and affinity outcomes because of the hands-on, outdoor qualities of the lab or because the format allowed greater interaction among peers and teaching instructors (TAs). To mitigate disparities in student learning outcomes between the online and in-person course delivery, instructors will implement future changes to the online version of the lab to enhance interactions among students and TAs. 
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                            - Award ID(s):
- 1752995
- PAR ID:
- 10399087
- Date Published:
- Journal Name:
- Frontiers in Environmental Science
- Volume:
- 10
- ISSN:
- 2296-665X
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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