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  • The covalent nucleotide modifications within plant mRNAs: What we know, how we find them, and what should be done in the future
Title: The covalent nucleotide modifications within plant mRNAs: What we know, how we find them, and what should be done in the future
Abstract Although covalent nucleotide modifications were first identified on the bases of transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), a number of these epitranscriptome marks have also been found to occur on the bases of messenger RNAs (mRNAs). These covalent mRNA features have been demonstrated to have various and significant effects on the processing (e.g. splicing, polyadenylation, etc.) and functionality (e.g. translation, transport, etc.) of these protein-encoding molecules. Here, we focus our attention on the current understanding of the collection of covalent nucleotide modifications known to occur on mRNAs in plants, how they are detected and studied, and the most outstanding future questions of each of these important epitranscriptomic regulatory signals.  more » « less
Award ID(s):
1849708
PAR ID:
10434654
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
The Plant Cell
Volume:
35
Issue:
6
ISSN:
1040-4651
Page Range / eLocation ID:
1801 to 1816
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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  5. (, Journal of Biological Chemistry)
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