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Abstract Nonlinear electrokinetics (EK), specifically electrophoresis of the second kind, dielectrophoresis (DEP) and electrorotation (EROT), have gained significant interest recently for their flexibility and labeless discriminant manner of operation. The current applications of these technologies are a clear advancement from what they were when first discovered, but also still show strong signs of future growth. The present review article presents a discussion of the current uses of microscale nonlinear EK technologies as analytical, sensing, and purification tools for microorganisms. The discussion is focused on some of the latest discoveries with various nonlinear EK microfluidic techniques, such as DEP particle trapping and EROT for particle assessments, for the analysis of microorganisms ranging from viruses to parasites. Along the way, special focus was given to key research articles from within the past two years to provide the most up‐to‐date knowledge on the current state‐of‐the‐art within the field of microscale EK, and from there, an outlook on where the future of the field is headed is also included.
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This content will become publicly available on August 1, 2026
Dielectrophoresis in Carcinoma Diagnosis: Recent Developments and Applications
ABSTRACT Accurate cancer cell analysis is critical across a wide range of medical fields, including clinical diagnostics, personalized medicine, drug development, and cancer research. The ability to rapidly analyze and characterize cancer cells is key to understanding tumor characteristics, developing targeted therapies, and improving patient outcomes. Microscale electrokinetic (EK) techniques have demonstrated their effectiveness and reliability as powerful tools for cell analysis, including cancerous cells. The applications of dielectrophoresis (DEP), an EK technique, in cancer cell analysis are discussed here with a focus on carcinomas, cancer that develops in epithelial tissue. In this review article, the working mechanism of DEP is first introduced, followed by an in‐depth review of recent studies published between 2015 and 2024. The concluding remarks section provides a summary of the key points discussed in this review and offers insights into potential future advancements in DEP‐based systems for analyzing cancerous cells.
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- Award ID(s):
- 2127592
- PAR ID:
- 10655665
- Publisher / Repository:
- Wiley
- Date Published:
- Journal Name:
- ELECTROPHORESIS
- Volume:
- 46
- Issue:
- 16
- ISSN:
- 0173-0835
- Page Range / eLocation ID:
- 1246 to 1276
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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