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In collaboration with the Center for Microbiome Analysis through Island Knowledge and Investigations (C-MĀIKI), the Hawaii EPSCoR Ike Wai project and the Hawaii Data Science Institute, a new science gateway, the C-MĀIKI gateway, was developed to support modern, interoperable and scalable microbiome data analysis. This gateway provides a web-based interface for accessing high-performance computing resources and storage to enable and support reproducible microbiome data analysis. The C-MĀIKI gateway is accelerating the analysis of microbiome data for Hawaii through ease of use and centralized infrastructure.Free, publicly-accessible full text available July 8, 2023
Infectious pathogens can disrupt the microbiome in addition to directly affecting the host. Impacts of disease may be dependent on the ability of the microbiome to recover from such disturbance, yet remarkably little is known about microbiome recovery after disease, particularly in nonhuman animals. We assessed the resilience of the amphibian skin microbial community after disturbance by the pathogen,
Batrachochytrium dendrobatidis(Bd). Skin microbial communities of laboratory-reared mountain yellow-legged frogs were tracked through three experimental phases: prior to Bd infection, after Bd infection (disturbance), and after clearing Bd infection (recovery period). Bd infection disturbed microbiome composition and altered the relative abundancesmore »
Abstract — SAGE (the Scalable Adaptive Graphics Environment) and its successor SAGE2 (the Scalable Amplified Group Environment) are operating systems for managing content across wideband display environments. This paper documents the prevalent usage patterns of SAGE-enabled display walls in support of the e-Science enterprise, based on nearly 15 years of observations of the SAGE community. These patterns will help guide e-Science users and cyberinfrastructure developers on how best to leverage large tiled display walls, and the types of software services that could be provided in the future.
Microbes have been critical drivers of evolutionary innovation in animals. To understand the processes that influence the origin of specialized symbiotic organs, we report the sequencing and analysis of the genome of
Euprymna scolopes, a model cephalopod with richly characterized host–microbe interactions. We identified large-scale genomic reorganization shared between E. scolopesand Octopus bimaculoidesand posit that this reorganization has contributed to the evolution of cephalopod complexity. To reveal genomic signatures of host–symbiont interactions, we focused on two specialized organs of E. scolopes: the light organ, which harbors a monoculture of Vibrio fischeri, and the accessory nidamental gland (ANG), a reproductive organ containing a bacterial consortium. Ourmore »