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Abstract The existence of three distinct neutrino flavours,ν_e,ν_μandν_τ, is a central tenet of the Standard Model of particle physics^1,2. Quantum-mechanical interference can allow a neutrino of one initial flavour to be detected sometime later as a different flavour, a process called neutrino oscillation. Several anomalous observations inconsistent with this three-flavour picture have motivated the hypothesis that an additional neutrino state exists, which does not interact directly with matter, termed as ‘sterile’ neutrino,ν_s(refs. ^3–9). This includes anomalous observations from the Liquid Scintillator Neutrino Detector (LSND)³experiment and Mini-Booster Neutrino Experiment (MiniBooNE)^4,5, consistent withν_μ → ν_etransitions at a distance inconsistent with the three-neutrino picture. Here we use data obtained from the MicroBooNE liquid-argon time projection chamber¹⁰in two accelerator neutrino beams to exclude the single light sterile neutrino interpretation of the LSND and MiniBooNE anomalies at the 95% confidence level (CL). Moreover, we rule out a notable portion of the parameter space that could explain the gallium anomaly^6–8. This is one of the first measurements to use two accelerator neutrino beams to break a degeneracy betweenν_eappearance and disappearance, which would otherwise weaken the sensitivity to the sterile neutrino hypothesis. We find no evidence for eitherν_μ → ν_eflavour transitions orν_edisappearance that would indicate non-standard flavour oscillations. Our results indicate that previous anomalous observations consistent withν_μ → ν_etransitions cannot be explained by introducing a single sterile neutrino state. 

This Letter presents an investigation of low-energy electron-neutrino interactions in the Fermilab Booster Neutrino Beam by the MicroBooNE experiment, motivated by the excess of electron-neutrino-like events observed by the MiniBooNE experiment. This is the first measurement to use data from all five years of operation of the MicroBooNE experiment, corresponding to an exposure of $1.11\times {10}^{21}$protons on target, a 70% increase on past results. Two samples of electron neutrino interactions without visible pions are used, one with visible protons and one without any visible protons. The MicroBooNE data show reasonable agreement with the nominal prediction, with $p$values $\ge 26.7\%$when the two ${\nu }_e$samples are combined, though the prediction exceeds the data in limited regions of phase space. The data are further compared to two empirical models that modify the predicted rate of electron-neutrino interactions in different variables in the simulation to match the unfolded MiniBooNE low energy excess. In the first model, this unfolding is performed as a function of electron neutrino energy, while the second model aims to match the observed shower energy and angle distributions of the MiniBooNE excess. This measurement excludes an electronlike interpretation of the MiniBooNE excess based on these models at $>99\%{\mathrm{CL}}_{\mathrm{s}}$in all kinematic variables. 

Charged-current neutrino interactions with final states containing zero mesons and at least one proton are of high interest for current and future accelerator-based neutrino oscillation experiments. Using the Booster Neutrino Beam and the MicroBooNE detector at Fermi National Accelerator Laboratory, we have obtained the first double-differential cross-section measurements of this channel for muon neutrino scattering on an argon target with a leading proton momentum threshold of $0.25\mathrm{GeV}/c$. We also report a flux-averaged total cross section of $\sigma =(11.8\pm 1.2)\times {10}^{-38}{\mathrm{cm}}^2/\mathrm{Ar}$and several single-differential measurements which extend and improve upon previous results. Statistical and systematic uncertainties are quantified with a full treatment of correlations across 359 kinematic bins, including correlations between distributions describing different observables. The resulting dataset provides the most detailed information obtained to date for testing models of mesonless neutrino-argon scattering. 

Neutrino-nucleus cross section measurements are needed to improve interaction modeling to meet the precision needs of neutrino experiments in efforts to measure oscillation parameters and search for physics beyond the Standard Model. We review the difficulties associated with modeling neutrino-nucleus interactions that lead to a dependence on event generators in oscillation analyses and cross section measurements alike. We then describe data-driven model validation techniques intended to address this model dependence. The method relies on utilizing various goodness-of-fit tests and the correlations between different observables and channels to probe the model for defects in the phase space relevant for the desired analysis. These techniques shed light on relevant mismodeling, allowing it to be detected before it begins to bias the cross section results. We compare more commonly used model validation methods which directly validate the model against alternative ones to these data-driven techniques and show their efficacy with fake data studies. These studies demonstrate that employing data-driven model validation in cross section measurements represents a reliable strategy to produce robust results that will stimulate the desired improvements to interaction modeling. Published by the American Physical Society2025 

We present the measurement of ${\pi }^{+}$-argon inelastic cross sections using the ProtoDUNE single-phase liquid argon time projection chamber in the incident ${\pi }^{+}$kinetic energy range of 500–800 MeV in multiple exclusive channels (absorption, charge exchange, and the remaining inelastic interactions). The results of this analysis are important inputs to simulations of liquid argon neutrino experiments such as the Deep Underground Neutrino Experiment and the Short Baseline Neutrino program at Fermi National Accelerator Laboratory. They will be employed to improve the modeling of final state interactions within neutrino event generators used by these experiments, as well as the modeling of ${\pi }^{+}$-argon secondary interactions within the liquid argon. This is the first measurement of ${\pi }^{+}$-argon absorption at this kinetic energy range as well as the first ever measurement of ${\pi }^{+}$-argon charge exchange. 

We present a search for long-lived particles (LLPs), produced in kaon decays, that decay to two muons inside the ICARUS neutrino detector. This channel would be a signal of hidden sector models that can address outstanding issues in particle physics such as the strong CP problem and the microphysical origin of dark matter. The search is performed with data collected in the Neutrinos at the Main Injector (NuMI) beam at Fermilab corresponding to $2.41\times {10}^{20}$protons-on-target. No new physics signal is observed, and we set world leading limits on heavy QCD axions, as well as for the Higgs portal scalar among dedicated searches. Limits are also presented in a model-independent way applicable to any new physics model predicting the process $K\to \pi +S(\to \mu \mu )$, for a LLP $S$. This result is the first search for new physics performed with the ICARUS detector at Fermilab. It paves the way for the future program of LLP searches at ICARUS. Published by the American Physical Society2025 

We report the first double-differential cross section measurement of neutral-current neutral pion ( $\mathrm{NC}{\pi }^0$) production in neutrino-argon scattering, as well as single-differential measurements of the same channel in terms of final states with and without protons. The kinematic variables of interest for these measurements are the ${\pi }^0$momentum and the ${\pi }^0$scattering angle with respect to the neutrino beam. A total of 4971 candidate $\mathrm{NC}{\pi }^0$events fully contained within the MicroBooNE detector are selected using data collected at a mean neutrino energy of $\sim 0.8\mathrm{GeV}$from $6.4\times {10}^{20}$protons on target from the Booster Neutrino Beam at the Fermi National Accelerator Laboratory. After extensive data-driven model validation to ensure unbiased unfolding, the Wiener-singular-value-decomposition method is used to extract nominal flux-averaged cross sections. The results are compared to predictions from commonly used neutrino event generators, which tend to overpredict the measured $\mathrm{NC}{\pi }^0$cross section, especially in the $0.2–0.5\mathrm{GeV}/\mathrm{c}$ ${\pi }^0$momentum range and at forward scattering angles. Events with at least one proton present in the final state are also underestimated. This data will help improve the modeling of $\mathrm{NC}{\pi }^0$production, which represents a major background in measurements of charge-parity violation in the neutrino sector and in searches for new physics beyond the standard model.