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Abstract Differential privacy is a mathematical concept that provides an information-theoretic security guarantee. While differential privacy has emerged as a de facto standard for guaranteeing privacy in data sharing, the known mechanisms to achieve it come with some serious limitations. Utility guarantees are usually provided only for a fixed, a priori specified set of queries. Moreover, there are no utility guarantees for more complex—but very common—machine learning tasks such as clustering or classification. In this paper we overcome some of these limitations. Working with metric privacy, a powerful generalization of differential privacy, we develop a polynomial-time algorithm that creates aprivate measurefrom a data set. This private measure allows us to efficiently construct private synthetic data that are accurate for a wide range of statistical analysis tools. Moreover, we prove an asymptotically sharp min-max result for private measures and synthetic data in general compact metric spaces, for any fixed privacy budget$$\varepsilon $$ $\epsilon$bounded away from zero. A key ingredient in our construction is a newsuperregular random walk, whose joint distribution of steps is as regular as that of independent random variables, yet which deviates from the origin logarithmically slowly. 

We present a highly effective algorithmic approach for generating ε-differentially private synthetic data in a bounded metric space with near-optimal utility guarantees under the 1-Wasserstein distance. 

High-dimensional multimodal data arises in many scientific fields. The integration of multimodal data becomes challenging when there is no known correspondence between the samples and the features of different datasets. To tackle this challenge, we introduce AVIDA, a framework for simultaneously performing data alignment and dimension reduction. In the numerical experiments, Gromov-Wasserstein optimal transport and t-distributed stochastic neighbor embedding are used as the alignment and dimension reduction modules respectively. We show that AVIDA correctly aligns high-dimensional datasets without common features with four synthesized datasets and two real multimodal single-cell datasets. Compared to several existing methods, we demonstrate that AVIDA better preserves structures of individual datasets, especially distinct local structures in the joint low-dimensional visualization, while achieving comparable alignment performance. Such a property is important in multimodal single-cell data analysis as some biological processes are uniquely captured by one of the datasets. In general applications, other methods can be used for the alignment and dimension reduction modules.