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Title: Post-polymerization modification of styrene–maleic anhydride copolymer brushes
Post-polymerization modification (PPM) has been broadly employed to achieve functional polymer brush surfaces via immobilization of functional moieties on the brush using efficient organic tranformations. Here, we demonstrate the amine-anhydride reaction as a modular PPM route to functional brush surfaces using poly(styrene–maleic anhydride) (pSMA) copolymer brushes as a platform. The amine-anhydride reaction on pSMA surfaces proceeds to high conversions, with rapid kinetics, under ambient reaction conditions, and exploits a readily available library of functional amines. Using cystamine as a modifier, a convenient route to thiol-functionalized brushes was developed that enables sequential PPM modifications with a large library of alkenes using both base-catalyzed thiol-Michael and radical-mediated thiol–ene reactions. The high fidelity PPM reactions were demonstrated via the development of multifunctional, micropatterned brush surfaces.  more » « less
Award ID(s):
1056817
NSF-PAR ID:
10058761
Author(s) / Creator(s):
; ; ; ; ; ;
Date Published:
Journal Name:
Polymer Chemistry
Volume:
8
Issue:
44
ISSN:
1759-9954
Page Range / eLocation ID:
6778 to 6785
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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