Genetic variations in the COVID-19 virus are one of the main causes of the COVID-19 pandemic outbreak in 2020 and 2021. In this article, we aim to introduce a new type of model, a system coupled with ordinary differential equations (ODEs) and measure differential equation (MDE), stemming from the classical SIR model for the variants distribution. Specifically, we model the evolution of susceptible
Many dynamical systems described by nonlinear ODEs are unstable. Their associated solutions do not converge towards an equilibrium point, but rather converge towards some invariant subset of the state space called an attractor set. For a given ODE, in general, the existence, shape and structure of the attractor sets of the ODE are unknown. Fortunately, the sublevel sets of Lyapunov functions can provide bounds on the attractor sets of ODEs. In this paper we propose a new Lyapunov characterization of attractor sets that is well suited to the problem of finding the minimal attractor set. We show our Lyapunov characterization is non-conservative even when restricted to Sum-of-Squares (SOS) Lyapunov functions. Given these results, we propose a SOS programming problem based on determinant maximization that yields an SOS Lyapunov function whose
- Award ID(s):
- 1931270
- Publication Date:
- NSF-PAR ID:
- 10354588
- Journal Name:
- Journal of Computational Dynamics
- Volume:
- 0
- Issue:
- 0
- Page Range or eLocation-ID:
- 0
- ISSN:
- 2158-2491
- Sponsoring Org:
- National Science Foundation
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and removed\begin{document}$ S $\end{document} populations by ODEs and the infected\begin{document}$ R $\end{document} population by a MDE comprised of a probability vector field (PVF) and a source term. In addition, the ODEs for\begin{document}$ I $\end{document} and\begin{document}$ S $\end{document} contains terms that are related to the measure\begin{document}$ R $\end{document} . We establish analytically the well-posedness of the coupled ODE-MDE system by using generalized Wasserstein distance. We give two examples to show that the proposed ODE-MDE model coincides with the classical SIR model in case of constant or time-dependent parameters as special cases.\begin{document}$ I $\end{document} -
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